General
Preferred name
MAROPITANT
Synonyms
MAROPITANT CITRATE ()
Prevomax ()
CJ-11972 ()
Maropitant citrate monohydrate ()
Cerenia ()
CJ-11,972 ()
P&D ID
PD013044
CAS
359875-09-5
147116-67-4
Tags
available
drug candidate
drug
Approved by
FDA
Drug Status
vet_approved
approved
investigational
Max Phase
2.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Maropitant is an orally active NK1 receptor antagonist. Maropitant prevents vomiting and inhibits ulcerative dermatitis[1][2].
PRICE
69
PRICE
200
DESCRIPTION
Maropitant citrate is a synthetic neurokinin-1 receptor antagonist and substance P inhibitor, used for controlling vomiting in cats and dogs.
DESCRIPTION
Maropitant is a neurokinin (NK1) receptor antagonist.
(BOC Sciences Bioactive Compounds)
DESCRIPTION
Maropitant is a selective neurokinin (NK1) receptor antagonist.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
10
BOC Sciences Bioactive Compounds
Cayman Chemical Bioactives
ChEMBL Drugs
Drug Repurposing Hub
DrugBank
DrugBank Approved Drugs
DrugCentral
MedChem Express Bioactive Compound Library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
31
Molecular Weight
468.31
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
1
Rotatable Bonds
7
Ring Count
6
Aromatic Ring Count
3
cLogP
6.38
TPSA
24.5
Fraction CSP3
0.44
Chiral centers
2.0
Largest ring
6.0
QED
0.44
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Neurokinin Receptor
NK1
TACR1
Indication
vomiting
MOA
neurokinin receptor antagonist
Pathway
GPCR/G protein
Neuroscience
Neuronal Signaling
Source data
