General
Preferred name
RGDS peptide
Synonyms
Fibronectin tetrapeptide ()
Arg-Gly-Asp-Ser ()
DU-728 ()
RGDS Peptide ()
P&D ID
PD012993
CAS
91037-65-9
Tags
available
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Hdm2 inhibitor; activates p53-dependent transcription (Tocris Bioactive Compound Library)
Cell lines
1
Organisms
1
Compound Sets
5
Cayman Chemical Bioactives
15359
Drug Repurposing Hub
MedChem Express Bioactive Compound Library
HY-12290
ReFrame library
Tocris Bioactive Compound Library
3498
External IDs
21
Properties
(calculated by RDKit )
Molecular Weight
433.19
Hydrogen Bond Acceptors
8
Hydrogen Bond Donors
10
Rotatable Bonds
14
Ring Count
0
Aromatic Ring Count
0
cLogP
-4.79
TPSA
270.05
Fraction CSP3
0.6
Chiral centers
3.0
Largest ring
0.0
QED
0.07
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Primary Target
Integrins
MOA
Inhibitor
structural glycoprotein antagonist
Target
ITGA2B, ITGB3
Integrin
Pathway
cytoskeleton
Source data