General
Preferred name
CL-387785
Synonyms
CL 387785 ()
WAY-EKI 785 ()
EKI-785 ()
CL387785 ()
CL-387785 (EKI-785) ()
P&D ID
PD012958
CAS
194423-06-8
Tags
drug candidate
covalent binder
probe
available
Drug indication
Discovery agent
Probe info
Probe selectivity
protein-selective
Probe type
P&D approved
calculated probe
Probe sources
Probe targets
[[ compound.targets[t].gene_name ]]
Probe control
Orthogonal probes
78
No orthogonal probes found
Similar probes
33
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
3
Organisms
1
Compound Sets
8
AdooQ Bioactive Compound Library
Cayman Chemical Bioactives
CovalentInDB
DrugMAP
MedChem Express Bioactive Compound Library
Probe Miner (suitable probes)
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
17
Properties
(calculated by RDKit )
Molecular Weight
380.03
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
2
Rotatable Bonds
3
Ring Count
3
Aromatic Ring Count
3
cLogP
4.1
TPSA
66.91
Fraction CSP3
0.06
Chiral centers
0.0
Largest ring
6.0
QED
0.67
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Angiogenesis
JAK/STAT Signaling
Tyrosine Kinase/Adaptors
Protein Tyrosine Kinase/RTK
Target
EGFR
Source data
