General
Preferred name
Oseltamivir Acid
Synonyms
Oseltamivir acid tartrate ()
GS4071 ()
Oseltamivir acid (hydrochloride) ()
GS 4071 ()
Ro 64-0802 ()
oseltamivir carboxylate ()
GS 4071 (hydrochloride) ()
Ro 64-0802 (hydrochloride) ()
Oseltamivir carboxylate (hydrochloride) ()
GS-4071 ()
RO-640802 ()
Oseltamivir free acid ()
RO-64-0802 ()
Oseltamivir acid ()
Oseltamivir acid, (-)- ()
OSELTAMIVIR CARBOXYLATE HYDROCHLORIDE ()
Oseltamivir acid tartrate salt ()
P&D ID
PD012877
CAS
187227-45-8
1215211-48-5
1415963-60-8
Tags
available
drug
Drug indication
Discovery agent
Drug Status
approved
experimental
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Oseltamivir acid (GS 4071), the active metabolite of Oseltamivir phosphate, is an orally bioavailable, potent and selective inhibitor of influenza virus neuraminidase (IC50=2 nM) with activity against both influenza A and B viruses[1][2].
DESCRIPTION
Oseltamivir acid hydrochloride is an active metabolite of the antiviral agent Oseltamivir (HY-13317) ethylester. Oseltamivir acid hydrochloride belongs to baseline toxicants in toxicity ratio analysis[1].
DESCRIPTION
Oseltamivir acid is an antiviral prodrug targeted against the influenza viruses. It is an inhibitor of influenza neuraminidase.
(Enamine Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
0
Organisms
6
Compound Sets
10
Cayman Chemical Bioactives
ChEMBL Drugs
Drug Repurposing Hub
DrugBank
DrugMAP
Enamine Bioactive Compounds
Enamine BioReference Compounds
EU-OPENSCREEN Bioactive Compound Library
NCATS Inxight Approved Drugs
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
40
Molecular Weight
284.17
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
3
Rotatable Bonds
6
Ring Count
1
Aromatic Ring Count
0
cLogP
0.81
TPSA
101.65
Fraction CSP3
0.71
Chiral centers
3.0
Largest ring
6.0
QED
0.67
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
MOA
Influenza Virus
neuraminidase inhibitor
Indication
influenza A virus infection
Target
Drug Metabolite
Pathway
Anti-infection
Metabolic Enzyme/Protease
Source data
