General
Preferred name
Angiotensin 1-7
Synonyms
Ang-(1-7) ()
ASP-ARG-VAL-TYR-ILE-HIS-PRO ()
angiotensin-(1-7) ()
Talfirastide ()
Talfirastide (acetate) ()
Angiotensin (1-7) ()
TXA127 ()
TXA127 (acetate) ()
Angiotensin (1-7) (acetate) ()
Ang-(1-7) (acetate) ()
Ang-(1-7), Angiotensin fragment 1-7 ()
[125I]angiotensin-(1-7) (human, mouse, rat) ()
Bf-angiotensin 1-7 ()
Sh-heptapeptide-13 ()
TXA-127 ()
Angiotensin peptide (1-7) ()
5-ile-angiotensin-(1-7) ()
Human angiotensin ii (1-7) ()
Angiotensin fragment 1-7 ()
Angiotensin Fragment 1-7 (acetate) ()
P&D ID
PD012852
CAS
51833-78-4
39386-80-6
2855063-75-9
Tags
available
drug candidate
biased GPCR ligand
Drug indication
Chemotherapy-induced nausea
Duchenne dystrophy
Muscular dystrophy
Lymphoma
Sarcoma
Drug Status
investigational
Max Phase
Phase 2
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Ang 1-7 is cleaved from angiotensin 1 or angiotensin 2 by the actions of enzymes ACE2 and MME respectively
DESCRIPTION Angiotensin (1-7) is a naturally occurring peptide that is cleaved from angiotensin 1 or angiotensin 2 by the actions of the enzymes ACE2 and MME respectively. (GtoPdb)
Compound Sets
12
BiasDB
Ang(1-7)
Cayman Chemical Bioactives
17594
ChEMBL Drugs
CHEMBL3545347
Drug Repurposing Hub
DrugBank
DB11720
DrugMAP
DM76GZ0
EU-OPENSCREEN Bioactive Compound Library
EOS100380
Guide to Pharmacology
5578
582
MedChem Express Bioactive Compound Library
HY-12403
HY-12403A
ReFrame library
Selleckchem Bioactive Compound Library
angiotensin-1-7
TargetMol Bioactive Compound Library
T7339
External IDs
36
Properties
(calculated by RDKit )
Molecular Weight
898.47
Hydrogen Bond Acceptors
12
Hydrogen Bond Donors
13
Rotatable Bonds
25
Ring Count
3
Aromatic Ring Count
2
cLogP
-1.83
TPSA
377.24
Fraction CSP3
0.56
Chiral centers
8.0
Largest ring
6.0
QED
0.03
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Endocrinology/Hormones
GPCR/G protein
Metabolic Enzyme/Protease
Target
ACE
Angiotensin Receptor
Angiotensin-converting Enzyme (ACE)
Endogenous Metabolite
ACE,RAAS
MOA
angiotensin receptor agonist
Source data