General
Preferred name
INDACATEROL MALEATE
Synonyms
QAB149 ()
Indacaterol (maleate) ()
Indacaterol maleate component of ultibro ()
Hirobriz breezhaler ()
Indacaterol maleate component of utibron ()
QAB149-AFA ()
QAB-149-AFA ()
Onbrez Breezhaler ()
Arcapta Neohaler ()
Indacterol maleate ()
Oslif breezhaler ()
Indacaterol (as maleate) ()
Indacaterol maleate component of qva149 ()
Indacaterol maleate component of qva-149 ()
P&D ID
PD012764
CAS
753498-25-8
Tags
available
drug
Drug Status
approved
Max Phase
4.0
Drug indication
Chronic obstructive pulmonary disease
First approval
2009
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Indacaterol maleate (QAB149) is an orally active ultra-long-acting ¦Â2 adrenergic receptor (ADRB2) agonist. Indacaterol maleate inhibits NF-¦ÊB activity in a ¦Â-arrestin2-dependent manner, preventing further lung damage and improving lung function in COPD (chronic obstructive pulmonary disorder). Indacaterol maleate can also be used in cardiovascular disease research[1][2].
PRICE
30
DESCRIPTION
Indacaterol maleate (QAB149) is an ultra-long-acting ??-adrenoceptor agonist.
DESCRIPTION
Indacaterol maleate (QAB149) is an ultra-long-acting β-adrenoceptor agonist.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
5
ChEMBL Approved Drugs
ChEMBL Drugs
MedChem Express Bioactive Compound Library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
15
Molecular Weight
508.22
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
6
Rotatable Bonds
8
Ring Count
4
Aromatic Ring Count
3
cLogP
2.86
TPSA
159.95
Fraction CSP3
0.32
Chiral centers
1.0
Largest ring
6.0
QED
0.25
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Adrenergic Receptor
β1-adrenoceptor
β2-adrenoceptor
Pathway
GPCR/G protein
Neuroscience
Neuronal Signaling
Source data
