General
Preferred name
RASAGILINE MESYLATE
Synonyms
AGN1135 (mesylate) ()
TVP1012 ()
AGN1135 ()
AZILECT ()
Rasagiline (mesylate) ()
(R)-AGN1135 (mesylate) ()
TVP1012 (mesylate) ()
TVP-1012,(R)-AGN1135 mesylate,TVP1012 mesylate ()
RASAGILINE MESILATE ()
Rasagline ratiopharm ()
Rasagiline (as mesilate) ()
TVP-1012 ()
Rasagiline ratiopharm ()
Agilect ()
Rasagiline mesylate ()
P&D ID
PD012743
CAS
161735-79-1
Tags
available
covalent binder
drug
Drug Status
approved
Max Phase
4.0
Drug indication
multiple system atrophy
First approval
2005
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE
29
DESCRIPTION
Rasagiline mesylate is an amine oxidase B inhibitor. It is used for the treatment of idiopathic Parkinson's disease.
(Enamine Bioactive Compounds)
DESCRIPTION
Selective, irreversible MAO-B inhibitor
(Tocriscreen Plus)
DESCRIPTION
Rasagiline Mesylate (AGN1135) is a novel MAO-B inhibitor, which can treat idiopathic Parkinson's disease.
(TargetMol Bioactive Compound Library)
DESCRIPTION
Selective inhibitor of myosin light chain kinase
(Tocris Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
12
AdooQ Bioactive Compound Library
ChEMBL Approved Drugs
ChEMBL Drugs
CovalentInDB
Enamine Bioactive Compounds
Enamine BioReference Compounds
LSP-MoA library (Laboratory of Systems Pharmacology)
MedChem Express Bioactive Compound Library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
Tocris Bioactive Compound Library
Tocriscreen Plus
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
18
Molecular Weight
267.09
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
2
Rotatable Bonds
2
Ring Count
2
Aromatic Ring Count
1
cLogP
1.4
TPSA
66.4
Fraction CSP3
0.38
Chiral centers
1.0
Largest ring
6.0
QED
0.63
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target Type
Enzymes
Pathway
Apoptosis
Autophagy
Metabolism
Neuroscience
Neuronal Signaling
Primary Target
Monoamine Oxidases
MOA
Inhibitor
Target
Monoamine Oxidase
MAO
MAO-A
MAO-B
Source data
