General
Preferred name
RASAGILINE MESYLATE
Synonyms
AGN1135 (mesylate) ()
TVP1012 ()
AGN1135 ()
AZILECT ()
(R)-AGN1135 (mesylate) ()
TVP1012 (mesylate) ()
Rasagiline (mesylate) ()
TVP-1012,(R)-AGN1135 mesylate,TVP1012 mesylate ()
Agilect ()
TVP-1012 ()
Rasagline ratiopharm ()
RASAGILINE MESILATE ()
Rasagiline (as mesilate) ()
Rasagiline mesylate ()
P&D ID
PD012743
CAS
161735-79-1
Tags
available
drug
natural product
covalent binder
Drug Status
approved
Max Phase
4.0
Drug indication
Antiparkinsonian
First approval
2006
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Selective, irreversible MAO-B inhibitor
(Tocriscreen Plus)
DESCRIPTION
Selective inhibitor of myosin light chain kinase
(Tocris Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
11
AdooQ Bioactive Compound Library
ChEMBL Approved Drugs
ChEMBL Drugs
CovalentInDB
Enamine BioReference Compounds
LSP-MoA library (Laboratory of Systems Pharmacology)
MedChem Express Bioactive Compound Library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
Tocris Bioactive Compound Library
Tocriscreen Plus
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
17
Molecular Weight
267.09
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
2
Rotatable Bonds
2
Ring Count
2
Aromatic Ring Count
1
cLogP
1.4
TPSA
66.4
Fraction CSP3
0.38
Chiral centers
1.0
Largest ring
6.0
QED
0.63
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target Type
Enzymes
Pathway
Metabolism
Neuroscience
Apoptosis
Autophagy
Neuronal Signaling
Target
MAO-A
MAO-B
Monoamine Oxidase
MAO
Primary Target
Monoamine Oxidases
MOA
Inhibitor
Source data
