General
Preferred name
RIMONABANT HYDROCHLORIDE
Synonyms
SR 141716A ()
SR 151716A ()
SR 141716 hydrochloride ()
Rimonabant (Hydrochloride) ()
SR 141716A (Hydrochloride) ()
P&D ID
PD012650
CAS
158681-13-1
168273-06-1
Tags
available
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Rimonabant Hydrochloride (SR 141716A Hydrochloride) is a highly potent and selective central cannabinoid receptor (CB1) antagonist with an Ki of 1.8 nM. Rimonabant Hydrochloride (SR 141716A Hydrochloride) also inhibits Mycobacterial membrane protein Large 3 (MMPL3).
PRICE 61
DESCRIPTION Rimonabant hydrochloride (SR 141716A) is a cannabinoid receptor antagonist, binding selectively to central cannabinoid receptors (CB1) with high affinity. (TargetMol Bioactive Compound Library)
Compound Sets
4
Axon Medchem Screening Library
1220
Ki Database
SR 141716A
MedChem Express Bioactive Compound Library
HY-14137
TargetMol Bioactive Compound Library
T1519
External IDs
14
Properties
(calculated by RDKit )
Molecular Weight
498.05
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
1
Rotatable Bonds
4
Ring Count
4
Aromatic Ring Count
3
cLogP
6.36
TPSA
50.16
Fraction CSP3
0.27
Chiral centers
0.0
Largest ring
6.0
QED
0.45
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Bacterial
CB
CB1
CB1 antagonist
Cannabinoid Receptor
MOA
Cannabinoid Receptor antagonist
Pathway
GPCR/G protein
Microbiology/virology
Anti-infection
Neuronal Signaling
Source data