General
Preferred name
BAM7
Synonyms
BAM 7 ()
P&D ID
PD012596
CAS
331244-89-4
Tags
available
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION BAM7 is a direct and selective activator of proapoptotic BAX with an IC50 of 3.3 ¦ÌM.
PRICE 55
DESCRIPTION BAM 7 is a direct and specific activator of proapoptotic Bax (EC50: 3.3 ??M).
DESCRIPTION BAM 7 is a direct and selective activator of proapoptotic Bax with EC50 of 3.3 μM. (BOC Sciences Bioactive Compounds)
DESCRIPTION BAM 7 is a direct and specific activator of proapoptotic Bax (EC50: 3.3 μM). (TargetMol Bioactive Compound Library)
DESCRIPTION Breast cancer stem cell inhibitor (Tocris Bioactive Compound Library)
Cell lines
1
Organisms
0
Compound Sets
11
AdooQ Bioactive Compound Library
A12907
Axon Medchem Screening Library
2185
BOC Sciences Bioactive Compounds
bam7-cas-331244-89-4-item-84-459021
Cayman Chemical Bioactives
14566
CZ-OPENSCREEN Bioactive Library
Drug Repurposing Hub
JUMP-Target 1 Compound Set
5754137
MedChem Express Bioactive Compound Library
HY-15341
Selleckchem Bioactive Compound Library
bam7
TargetMol Bioactive Compound Library
T2453
Tocris Bioactive Compound Library
4810
External IDs
16
Properties
(calculated by RDKit )
Molecular Weight
405.13
Hydrogen Bond Acceptors
7
Hydrogen Bond Donors
1
Rotatable Bonds
6
Ring Count
4
Aromatic Ring Count
3
cLogP
4.4
TPSA
79.18
Fraction CSP3
0.14
Chiral centers
0.0
Largest ring
6.0
QED
0.62
Structural alerts
1
imine_one_fives(89)
[#6]-1=[!#1]-[!#6&!#1]-[#6](-[#6]-1=[!#6&!#1;!R])=[#8]
PAINS Family B
Related compounds
Custom attributes
(extracted from source data)
Target
BAX
Bcl-2 Family
Bcl-2
MOA
Activator
BAX activator
Pathway
Apoptosis
Source data