General
Preferred name
SALINOMYCIN
Synonyms
Coxistac, Bio-cox ()
Salinomycin (sodium salt) ()
Procoxacin ()
SALINOMYCIN SODIUM ()
Sodium salinomycin ()
Salinomycin (from Streptomyces albus) ()
Coxistac, Bio-cox, Procoxacin ()
E716 ()
P&D ID
PD012551
CAS
55721-31-8
53003-10-4
Tags
natural product
drug
available
Drug Status
approved
vet_approved
Approved by
FDA
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Salinomycin is an ionophore antibacterial, from which was derived. It is primarily used in veterinary practice. Salinomycin has potent antimicrobial activity against Gram-positive bacteria and is inactive against Gram-negative bacteria . (GtoPdb)
Cell lines
22
Organisms
7
Compound Sets
10
Cayman Chemical Bioactives
ChEMBL Drugs
Drug Repurposing Hub
DrugBank
DrugBank Approved Drugs
DrugCentral
Guide to Pharmacology
MedChem Express Bioactive Compound Library
Other bioactive compounds
Selleckchem Bioactive Compound Library
External IDs
46
Properties
(calculated by RDKit )
Molecular Weight
750.49
Hydrogen Bond Acceptors
10
Hydrogen Bond Donors
4
Rotatable Bonds
12
Ring Count
5
Aromatic Ring Count
0
cLogP
6.19
TPSA
161.21
Fraction CSP3
0.9
Chiral centers
18.0
Largest ring
6.0
QED
0.17
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Target
¦Â-catenin
??catenin
antibiotic
Bacterial
Mitophagy
Parasite
Wnt
β-catenin
Wnt/beta-catenin
Indication
coccidiosis
Pathway
Anti-infection
Apoptosis
Autophagy
Stem Cell/Wnt
Source data