General
Preferred name
SALINOMYCIN
Synonyms
Coxistac, Bio-cox ()
Salinomycin (sodium salt) ()
Procoxacin ()
SALINOMYCIN SODIUM ()
Sodium salinomycin ()
Salinomycin (from Streptomyces albus) ()
Coxistac, Bio-cox, Procoxacin ()
E716 ()
P&D ID
PD012551
CAS
55721-31-8
53003-10-4
Tags
natural product
drug
available
Drug Status
approved
vet_approved
Approved by
FDA
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Salinomycin is an ionophore antibacterial, from which was derived. It is primarily used in veterinary practice. Salinomycin has potent antimicrobial activity against Gram-positive bacteria and is inactive against Gram-negative bacteria .
(GtoPdb)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
22
Organisms
7
Compound Sets
10
Cayman Chemical Bioactives
ChEMBL Drugs
Drug Repurposing Hub
DrugBank
DrugBank Approved Drugs
DrugCentral
Guide to Pharmacology
Other bioactive compounds
Selleckchem Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
46
Properties
(calculated by RDKit )
Molecular Weight
750.49
Hydrogen Bond Acceptors
10
Hydrogen Bond Donors
4
Rotatable Bonds
12
Ring Count
5
Aromatic Ring Count
0
cLogP
6.19
TPSA
161.21
Fraction CSP3
0.9
Chiral centers
18.0
Largest ring
6.0
QED
0.17
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Target
¦Â-catenin
??catenin
antibiotic
Bacterial
Mitophagy
Parasite
Wnt
β-catenin
Wnt/beta-catenin
Indication
coccidiosis
Pathway
Anti-infection
Apoptosis
Autophagy
Stem Cell/Wnt
Source data