General
Preferred name
BMS-303141
Synonyms
BMS 303141 ()
BMS303141 ()
P&D ID
PD012469
CAS
943962-47-8
Tags
available
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION BMS-303141 is a potent, cell-permeable ATP-citrate lyase (ACL) inhibitor with an IC50 of 0.13 ¦ÌM.
PRICE 73
DESCRIPTION BMS-303141 is an inhibitor of ATP-citrate lyase (ACLY) . (GtoPdb)
DESCRIPTION BMS-303141 is a potent ATP-citrate lyase (ACL) inhibitor (IC50: 0.13 uM, human recombinant ACL). (TargetMol Bioactive Compound Library)
Cell lines
1
Organisms
0
Compound Sets
11
AdooQ Bioactive Compound Library
A13807
Axon Medchem Screening Library
2506
Cayman Chemical Bioactives
16239
CZ-OPENSCREEN Bioactive Library
EU-OPENSCREEN Bioactive Compound Library
EOS100249
Guide to Pharmacology
12855
LSP-MoA library (Laboratory of Systems Pharmacology)
CHEMBL399379
MedChem Express Bioactive Compound Library
HY-16107
Selleckchem Bioactive Compound Library
bms303141
TargetMol Bioactive Compound Library
T2337
ZINC Tool Compounds
ZINC000028951410
External IDs
17
Properties
(calculated by RDKit )
Molecular Weight
423.01
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
2
Rotatable Bonds
5
Ring Count
3
Aromatic Ring Count
3
cLogP
5.18
TPSA
75.63
Fraction CSP3
0.05
Chiral centers
0.0
Largest ring
6.0
QED
0.59
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Target
ACL
ATP citrate lyase
ACL inhibitor
ATP-citrate lyase
Pathway
Metabolic Enzyme/Protease
Metabolism
Source data