General
Preferred name
LISINOPRIL
Synonyms
MK-521 dihydrate ()
Renacor ()
MK-521 (dihydrate)Lisinopril ()
Lisinopril (Zestril) ()
Lisinopril (dihydrate) ()
MK-521 (dihydrate) ()
Lisinopril dihydrate ()
Ranolip ()
Prinivil ()
Lisopress ()
Lisinopril component of prinzide ()
Lisinopril hydrate ()
Acemin ()
Carace ()
Zestril ()
NSC-751176 ()
NSC-758151 ()
MK-521 ()
Qbrelis ()
Lisinopril component of zestoretic ()
Lisinopril ()
P&D ID
PD012438
CAS
83915-83-7
Tags
available
drug
Drug Status
approved
Max Phase
4.0
Drug indication
Hypertension
First approval
1987
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE
29
DESCRIPTION
Lisinopril dihydrate (MK-521) is an orally bioavailable, long-acting angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
7
AdooQ Bioactive Compound Library
ChEMBL Approved Drugs
ChEMBL Drugs
EU-OPENSCREEN Bioactive Compound Library
MedChem Express Bioactive Compound Library
Prestwick Chemical Library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
16
Molecular Weight
441.25
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
4
Rotatable Bonds
12
Ring Count
2
Aromatic Ring Count
1
cLogP
-0.41
TPSA
195.96
Fraction CSP3
0.57
Chiral centers
3.0
Largest ring
6.0
QED
0.32
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
ACE
MRP1
Angiotensin-converting Enzyme (ACE)
MOA
MRP inhibitor
RAAS inhibitor
Pathway
Endocrinology/Hormones
Immunology/Inflammation
Metabolic Enzyme/Protease
Source data
