General
Preferred name
ADRENOSTERONE
Synonyms
(+)-Adrenosterone ()
ADRENOTERONE ()
P&D ID
PD012351
CAS
382-45-6
Tags
available
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Adrenosterone ((+)-Adrenosterone) is a competitive hydroxysteroid (11-beta) dehydrogenase 1 (HSD11¦Â1) inhibitor.;Adrenosterone is a steroid hormone with weak androgenic effect. Adrenosterone is a dietary supplement that can decrease fat and increase muscle mass. Adrenosterone acts as a suppressor of metastatic progression of human cancer cells[1][2][3].
Compound Sets
3
Drug Repurposing Hub
MedChem Express Bioactive Compound Library
HY-17462
Prestwick Chemical Library
External IDs
34
Properties
(calculated by RDKit )
Molecular Weight
300.17
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
0
Rotatable Bonds
0
Ring Count
4
Aromatic Ring Count
0
cLogP
3.27
TPSA
51.21
Fraction CSP3
0.74
Chiral centers
5.0
Largest ring
6.0
QED
0.69
Structural alerts
1
steroid_A(2)
[#8]=[#6]-4-[#6]-[#6]-[#6]-3-[#6]-2-[#6](=[#8])-[#6]-[#6]-1-[#6]-[#6]-[#6]-[#6]-1-[#6]-2-[#6]-[#6]-[#6]-3=[#6]-4
PAINS Family C
Related compounds
Custom attributes
(extracted from source data)
Target
HSD11B1, HSD11B2
Androgen Receptor
Endogenous Metabolite
MOA
11-beta hydroxysteroid dehydrogenase inhibitor
Pathway
Metabolic Enzyme/Protease
Vitamin D Related/Nuclear Receptor
Source data