General
Preferred name
NIFURATEL
Synonyms
NF 113 ()
SAP 113 ()
Methylmercadone ()
Inimur ()
SAP-113 ()
Macmiror ()
Magmilor ()
Polmiror ()
NF-113 ()
Omnes ()
P&D ID
PD012329
CAS
4936-47-4
Tags
available
drug
Drug Status
approved
experimental
investigational
Max Phase
2.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Nifuratel (NF 113) is an orally active broad-spectrum antibiotic with antiprotozoal, antibacterial, anticancer and anti-inflammatory activities, and has good inhibitory effects on Candida and Trichomonas. Nifuratel is also a STAT3 inhibitor, which significantly inhibits the growth and proliferation of human gastric cancer cells and induces apoptosis. In addition, Nifuratel also inhibits mast cell-mediated antigen hypersensitivity reactions and can be used in the study of IgE-mediated allergic diseases[1][2][3][4][5][6][7][8].
PRICE
29
DESCRIPTION
Nifuratel is an antimicrobial nitrofuran drug that exhibits antiprotozoal, antifungal and antibacterial activities. Please note that the structure to which the CAS number is assigned does not specify stereochemistry.
(GtoPdb)
DESCRIPTION
Nifuratel (SAP 113) is a local antiprotozoal and antifungal agent that may also be given orally.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
10
ChEMBL Drugs
CZ-OPENSCREEN Bioactive Library
DrugBank
DrugCentral
DrugCentral Approved Drugs
Guide to Pharmacology
MedChem Express Bioactive Compound Library
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
18
Molecular Weight
285.04
Hydrogen Bond Acceptors
7
Hydrogen Bond Donors
0
Rotatable Bonds
5
Ring Count
2
Aromatic Ring Count
1
cLogP
1.71
TPSA
98.18
Fraction CSP3
0.4
Chiral centers
1.0
Largest ring
5.0
QED
0.46
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Antibacterial
antibiotic
Bacterial
Parasite
Apoptosis
Fungal
Interleukin Related
STAT
TNF Receptor
Pathway
Microbiology/virology
Anti-infection
Immunology/Inflammation
JAK/STAT Signaling
Stem Cell/Wnt
Source data
