General
Preferred name
Daptomycin
Synonyms
LY146032 ()
P&D ID
PD012318
CAS
103060-53-3
Tags
natural product
drug
available
Approved by
PMDA
FDA
First approval
2003
Drug Status
investigational
approved
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
10
Cayman Chemical Bioactives
Drug Repurposing Hub
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
MedChem Express Bioactive Compound Library
NCATS Inxight Approved Drugs
ReFrame library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
16
Properties
(calculated by RDKit )
Molecular Weight
1619.71
Hydrogen Bond Acceptors
24
Hydrogen Bond Donors
22
Rotatable Bonds
35
Ring Count
4
Aromatic Ring Count
3
cLogP
-5.62
TPSA
702.02
Fraction CSP3
0.53
Chiral centers
13.0
Largest ring
31.0
QED
0.01
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
DNA Damage/DNA Repair
Anti-infection
Target
DNA synthesis
antibiotic
Bacterial
Indication
skin infections, endocarditis
MOA
bacterial cell wall synthesis inhibitor
Source data
