General
Preferred name
NATAMYCIN
Synonyms
Pimaricin ()
Tennecetin ()
Antibiotic A-5283 ()
NSC-759167 ()
INS-235 ()
Mycophyt ()
Myprozine ()
E235 ()
Pimaracin ()
CL-12625 ()
Natacyn ()
Pimafucin ()
Synogil ()
E-235 ()
INS NO.235 ()
Delvocid ()
CL 12,625 ()
P&D ID
PD012295
CAS
7681-93-8
Tags
natural product
drug
available
Approved by
FDA
First approval
1978
Drug Status
approved
Drug indication
Conjunctivitis
Antibacterial (ophthalmic)
Max Phase
Phase 4
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
13
Cayman Chemical Bioactives
ChEMBL Approved Drugs
ChEMBL Drugs
Drug Repurposing Hub
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
MedChem Express Bioactive Compound Library
NCATS Inxight Approved Drugs
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
30
Properties
(calculated by RDKit )
Molecular Weight
665.3
Hydrogen Bond Acceptors
13
Hydrogen Bond Donors
7
Rotatable Bonds
3
Ring Count
4
Aromatic Ring Count
0
cLogP
0.12
TPSA
230.99
Fraction CSP3
0.64
Chiral centers
14.0
Largest ring
24.0
QED
0.16
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Endocrinology/Hormones
Anti-infection
Metabolic Enzyme/Protease
Target
ER
antibiotic
Bacterial
Endogenous Metabolite
Fungal
MOA
Estrogen/progestogen Receptor inhibitor
fungal ergosterol inhibitor
Disease Area
ophthalmology, infectious disease
Indication
conjunctivitis, fungal keratosis, blepharitis
Therapeutic Class
Antifungal Agents
Source data
