General
Preferred name
DEOXYGUANOSINE
Synonyms
2'-Deoxy-D-guanosine ()
2'-Deoxyguanosine monohydrate ()
2'-Deoxyguanosine (hydrate) ()
2'-Deoxyguanosine ()
P&D ID
PD012291
CAS
116002-28-9
38559-49-8
961-07-9
312693-72-4
Tags
available
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE 29
DESCRIPTION 2'-Deoxyguanosine (Guanine deoxyriboside) is a purine nucleoside that is recognized by members of the 2'-dG-II family.2'-Deoxyguanosine has been associated with aging, mutation, and carcinogenesis, and is oxidized by molecular oxygen.
PRICE 29
DESCRIPTION 2'-Deoxyguanosine monohydrate (Guanine-2'-deoxyriboside) is a nucleoside consisting of the base guanine and the sugar deoxyribose. It is like guanosine, but with one oxygen atom removed. It is a nucleoside component of DNA. 2'-Deoxyguanosine monohydrate can be converted to 8-hydroxy-deoxyguanosine (8-OHdG) due to hydroxyl radical attack at the C8 of guanine. 8-OHdG is a sensitive marker of the DNA damage This damage, if left unrepaired, has been proposed to contribute to mutagenicity and cancer promotion.
Compound Sets
2
Cayman Chemical Bioactives
9002864
Selleckchem Bioactive Compound Library
2-deoxyguanosine-monohydrate
External IDs
64
Properties
(calculated by RDKit )
Molecular Weight
267.1
Hydrogen Bond Acceptors
8
Hydrogen Bond Donors
4
Rotatable Bonds
2
Ring Count
3
Aromatic Ring Count
2
cLogP
-1.66
TPSA
139.28
Fraction CSP3
0.5
Chiral centers
3.0
Largest ring
6.0
QED
0.51
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
DNA/RNA Synthesis
Source data