General
Preferred name
Adjudin
Synonyms
AF-2364 ()
P&D ID
PD012269
CAS
252025-52-8
Tags
available
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Adjudin is an extensively studied male contraceptive with a superior mitochondria-inhibitory effect. Adjudin is also a potent Cl- channel blocker.
PRICE 57
DESCRIPTION Adjudin (AF-2364) is a small molecule compound known to possess antispermatogenic function, attenuates microglia activation by suppression of the NF-??B pathway.
DESCRIPTION Adjudin (AF-2364) is a small molecule compound known to possess antispermatogenic function, attenuates microglia activation by suppression of the NF-κB pathway. (TargetMol Bioactive Compound Library)
Compound Sets
6
AdooQ Bioactive Compound Library
A16303
Axon Medchem Screening Library
2552
Cayman Chemical Bioactives
22939
MedChem Express Bioactive Compound Library
HY-18996
Selleckchem Bioactive Compound Library
adjudin
TargetMol Bioactive Compound Library
T2498
External IDs
15
Properties
(calculated by RDKit )
Molecular Weight
334.04
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
2
Rotatable Bonds
3
Ring Count
3
Aromatic Ring Count
3
cLogP
2.99
TPSA
72.94
Fraction CSP3
0.07
Chiral centers
0.0
Largest ring
6.0
QED
0.44
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Target
Chloride channel
Mitochondrial Metabolism
Male contraceptive
Chloride Channel,ERK,NF-¦ÊB
MOA
Chloride Channel
Pathway
Membrane Transporter/Ion Channel
Metabolism
Metabolic Enzyme/Protease
Source data