General
Preferred name
FURAZIDIN
Synonyms
F-35 ()
Akritoin ()
Furazidine ()
NF-416 ()
Furagin ()
NF-416, F-35, Akritoin, Furazidin, Furazidine ()
Furaginum ()
P&D ID
PD012177
CAS
1672-88-4
Tags
available
drug candidate
Drug Status
experimental
Drug indication
bacterial disease
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Furagin (Furazidine), an analogue of Nitrofurantoin (HY-A0090), is an antibiotic with antibacterial activity against ESKAPE pathogens with MIC values of 0-32 ¦Ìg/mL. Furagin inhibits human Carbonic anhydrases . Furagin is promising for research of cancer and urinary tract infections (UTIs)[1][2][3][4][5].
PRICE 29
DESCRIPTION Furagin (a nitrofurantoin analog) has the same efficacy in treating acute cystitis as Ciprofloxacin, however the duration of therapy is longer. Antibacterial. (BOC Sciences Bioactive Compounds)
DESCRIPTION Furagin (Furazidine) is a Nitrofuran derivative with anti-infective activity used for urinary tract infections. (TargetMol Bioactive Compound Library)
Compound Sets
8
BOC Sciences Bioactive Compounds
furagin-cas-1672-88-4-item-84-395485
ChEMBL Drugs
CHEMBL3707254
CZ-OPENSCREEN Bioactive Library
Drug Repurposing Hub
DrugBank
DB13475
MedChem Express Bioactive Compound Library
HY-77036
Selleckchem Bioactive Compound Library
furagin
TargetMol Bioactive Compound Library
T4273
External IDs
17
Properties
(calculated by RDKit )
Molecular Weight
264.05
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
1
Rotatable Bonds
4
Ring Count
2
Aromatic Ring Count
1
cLogP
0.74
TPSA
118.05
Fraction CSP3
0.1
Chiral centers
0.0
Largest ring
5.0
QED
0.37
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Antibacterial
Bacterial
antibiotic
Carbonic Anhydrase
Pathway
Microbiology/virology
Anti-infection
Metabolic Enzyme/Protease
Source data