General
Preferred name
ETHISTERONE
Synonyms
Pregneninolone ()
17??-Ethynyltestosterone ()
17¦Á-Ethynyltestosterone ()
Anhydrohydroxyprogesterone ()
Ora-Lutin ()
Syngestrotabs ()
Trosinone ()
NSC-9565 ()
Pranone ()
P&D ID
PD012137
CAS
434-03-7
Tags
natural product
drug
available
Drug indication
Discovery agent
Drug Status
investigational
approved
Max Phase
Phase 3
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Ethisterone is a progestogen hormone being considered to treat prostate cancer.It was the first orally-active progestin. (BOC Sciences Bioactive Compounds)
Compound Sets
13
BOC Sciences Bioactive Compounds
ethisterone-cas-434-03-7-item-84-68796
Cayman Chemical Bioactives
22893
ChEMBL Drugs
CHEMBL241694
Drug Repurposing Hub
DrugCentral
1084
DrugCentral Approved Drugs
1084
DrugMAP
DMDXRP1
EU-OPENSCREEN Bioactive Compound Library
EOS102169
LSP-MoA library (Laboratory of Systems Pharmacology)
CHEMBL241694
NPC Screening Collection
Prestwick Chemical Library
Selleckchem Bioactive Compound Library
ethisterone
TargetMol Bioactive Compound Library
T0301
External IDs
31
Properties
(calculated by RDKit )
Molecular Weight
312.21
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
1
Rotatable Bonds
0
Ring Count
4
Aromatic Ring Count
0
cLogP
3.88
TPSA
37.3
Fraction CSP3
0.76
Chiral centers
6.0
Largest ring
6.0
QED
0.69
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Endocrinology/Hormones
Target
ER
TYR
Estrogen/progestogen Receptor
MOA
Estrogen/Progestogen Receptor agonist
progestogen hormone
Indication
amenorrhea
Source data