General
Preferred name
BRIMONIDINE TARTRATE
Synonyms
UK 14304 (tartrate) ()
AGN190342 (tartrate) ()
UK14304 tartrate ()
AGN190342 tartrate ()
UK 14,304 tartrate ()
Brimonidine L-Tartrate ()
AGN190342 (tartrate)UK 14304 (tartrate)304 tartrate ()
Brominide tartrate ()
Brimonidine (tartrate) ()
Alphagan p ()
Cd-07805 ()
UK-14304-18 ()
Lumify preservative free ()
CD-07805/47 ()
AGN 190342-LF ()
UK-1430418 ()
OCU300 ()
Brimonidine tartrate component of simbrinza ()
Brymont ()
OCU-300 ()
CD07805/47 ()
AGN-190342LF ()
Alphagan ()
Qoliana ()
Bromoxidine tartrate ()
Mirvaso ()
Brimonidine d-tartrate ()
Brimonidine tartrate component of combigan ()
AGN-190342-LF ()
Lumify ()
BRIMONIDINE ()
ALPHAGAN ()
ALPHAGAN P ()
BRIMONIDINE D-TARTRATE ()
BRIMONIDINE TARTRATE COMPONENT OF COMBIGAN ()
BRIMONIDINE TARTRATE COMPONENT OF SIMBRINZA ()
BROMOXIDINE TARTRATE ()
BRYMONT ()
CD-07805 ()
LUMIFY ()
LUMIFY PRESERVATIVE FREE ()
MIRVASO ()
QOLIANA ()
P&D ID
PD012111
CAS
109826-56-4
79570-19-7
70359-46-5
Tags
available
drug
Drug indication
Discovery agent
Open-angle glaucoma
Drug Status
approved
Max Phase
4.0
First approval
1996
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE 29
DESCRIPTION Brimonidine tartrate (UK 14304 tartrate) is a full ¦Á2-adrenergic receptor (¦Á2-AR) agonist.
DESCRIPTION Brimonidine Tartrate (AGN190342 tartrate) is a quinoxaline derivative and adrenergic ??-2 receptor agonist (EC50: 0.45 nM) that is used to manage intraocular pressure associated with open-angle glaucoma or ocular hypertension.
DESCRIPTION Brimonidine Tartrate (AGN190342 tartrate) is a quinoxaline derivative and adrenergic α-2 receptor agonist (EC50: 0.45 nM) that is used to manage intraocular pressure associated with open-angle glaucoma or ocular hypertension. (TargetMol Bioactive Compound Library)
Compound Sets
11
Axon Medchem Screening Library
1555
Cayman Chemical Bioactives
15426
ChEMBL Approved Drugs
CHEMBL1200389
ChEMBL Drugs
CHEMBL1200389
CZ-OPENSCREEN Bioactive Library
DrugMAP
DMMC4BY
EU-OPENSCREEN Bioactive Compound Library
EOS101194
EUbOPEN Chemogenomics Library
EUB0000886
MedChem Express Bioactive Compound Library
HY-B0659A
Prestwick Chemical Library
TargetMol Bioactive Compound Library
T6422
External IDs
14
Properties
(calculated by RDKit )
Molecular Weight
441.03
Hydrogen Bond Acceptors
9
Hydrogen Bond Donors
6
Rotatable Bonds
4
Ring Count
3
Aromatic Ring Count
2
cLogP
-0.36
TPSA
177.26
Fraction CSP3
0.27
Chiral centers
2.0
Largest ring
6.0
QED
0.37
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Adrenergic Receptor
α2A-adrenergic receptor
¦Á2A-adrenergic receptor
a2 agonist
MOA
Adrenergic Receptor agonist
Pathway
GPCR/G protein
Neuroscience
Neuronal Signaling
Recommended Cell Concentration
100 nM
Source data