General
Preferred name
Acteoside
Synonyms
Kusaginin ()
TJC160 ()
Verbascoside ()
ACETOSIDE ()
Acteoside, Kusaginin ()
Verbacoside ()
P&D ID
PD012066
CAS
61276-17-3
22323-52-0
Tags
drug candidate
natural product
available
Drug indication
Nephritis
Drug Status
investigational
Max Phase
Phase 2
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Verbascoside (acteoside) is a plant-derived natural product. It acts as a TRPV3 channel blocker.
(GtoPdb)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
6
Organisms
2
Compound Sets
12
AdooQ Bioactive Compound Library
Cayman Chemical Bioactives
ChEMBL Drugs
Concise Guide to Pharmacology 2023/24
Drug Repurposing Hub
DrugBank
DrugMAP
Guide to Pharmacology
MedChem Express Bioactive Compound Library
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
25
Molecular Weight
624.21
Hydrogen Bond Acceptors
15
Hydrogen Bond Donors
9
Rotatable Bonds
10
Ring Count
4
Aromatic Ring Count
2
cLogP
-1.02
TPSA
245.29
Fraction CSP3
0.48
Chiral centers
10.0
Largest ring
6.0
QED
0.09
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Chromatin/Epigenetic
Apoptosis
Cytoskeletal Signaling
DNA Damage/DNA Repair
Anti-infection
Epigenetics
TGF-beta/Smad
Target
p53
PARP1
PKC
Bacterial
HSV
Immunology & Inflammation related
MOA
NFkB pathway inhibitor, PKC inhibitor
Source data
