General
Preferred name
POLIUMOSIDE
Synonyms
P&D ID
PD012064
CAS
94079-81-9
Tags
available
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Poliumoside, a caffeoylated phenylpropanoid glycoside, is isolated from Brandisia hancei stems and leaves. Poliumoside is an advanced glycation end product (AGE) formation and rat lens aldose reductase (RLAR) inhibitor, with IC50s of 19.69 and 8.47 ¦ÌM, respectively. Poliumoside also has antiinflammatory and antioxidant activity[1][2][3].
PRICE 230
DESCRIPTION Poliumoside is a natural compound which exhibits significant inhibition of advanced glycation end product formation with IC50 value of 4.6-25.7 ??M, it also exhibits great inhibitory effects on rat lens aldose reductase with IC50 values of 0.85 ??M.Poliumoside has oxidant scavenging, antibacterial and hemostasis capacities, it can inhibit Biofilm-forming Staphylococcus aureus in mice.
DESCRIPTION Poliumoside is a natural compound extracted from Beautyberry extract, which exhibit significant inhibition of advanced glycation end product formation. It exhibited greater inhibitory effects on rat lens aldose reductase than those of the positive controls, 3,3-tetramethyleneglutaric acid and quercetin. (BOC Sciences Bioactive Compounds)
DESCRIPTION Poliumoside is a natural compound which exhibits significant inhibition of advanced glycation end product formation with IC50 value of 4.6-25.7 μM, it also exhibits great inhibitory effects on rat lens aldose reductase with IC50 values of 0.85 μM.Poliumoside has oxidant scavenging, antibacterial and hemostasis capacities, it can inhibit Biofilm-forming Staphylococcus aureus in mice. (TargetMol Bioactive Compound Library)
Compound Sets
3
BOC Sciences Bioactive Compounds
poliumoside-cas-94079-81-9-item-84-286669
MedChem Express Bioactive Compound Library
HY-N0033
TargetMol Bioactive Compound Library
T6S2384
External IDs
10
Properties
(calculated by RDKit )
Molecular Weight
770.26
Hydrogen Bond Acceptors
19
Hydrogen Bond Donors
11
Rotatable Bonds
12
Ring Count
5
Aromatic Ring Count
2
cLogP
-2.16
TPSA
304.21
Fraction CSP3
0.57
Chiral centers
15.0
Largest ring
6.0
QED
0.06
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Aldose Reductase
Pathway
Endocrinology/Hormones
Metabolism
Metabolic Enzyme/Protease
Source data