General
Preferred name
ESTRADIOL BENZOATE
Synonyms
CHEMBL282575 ()
Benzoestrofol ()
Benzhormovarine ()
Benovocylin ()
β-Estradiol 3-benzoate ()
17β-Estradiol 3-benzoate ()
¦Â-Estradiol 3-benzoate ()
Benztrone ()
Benzoato de estradiol ()
Estradiol 3-benzoate ()
NSC-9566 ()
Progynon B Oleoso ()
Benzoate d'estradiol ()
17¦Â-Estradiol 3-benzoate ()
P&D ID
PD012021
CAS
50-50-0
Tags
available
probe
drug
Approved by
FDA
Drug Status
vet_approved
approved
investigational
Max Phase
2.0
Probe info
Probe type
P&D approved
calculated probe
Probe selectivity
protein-selective
Probe sources
Tool Compound Set
Probe targets
[[ compound.targets[t].gene_name ]]
Probe control
Probe control not defined
Orthogonal probes
92
No orthogonal probes found
Similar probes
1
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE
29
DESCRIPTION
Estradiol benzoate (¦Â-Estradiol 3-benzoate) is a HBx protein inhibitor and inhibits androgen and hepatitis B virus (HBV) transcription, replication. Estradiol benzoate shows antifertility effects, anti- Toxoplasma gondii activity and can improve memory behavior of Ovariectomy (Ovx) female mice[1][2][3][4][5].
DESCRIPTION
Estradiol benzoate is an estradiol analog which binds to the human, murine and chicken ERα with IC50 of 22-28 nM.
(BOC Sciences Bioactive Compounds)
DESCRIPTION
Estradiol benzoate (Benzhormovarine) is the synthetic benzoate ester of estradiol, a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
0
Organisms
3
Compound Sets
13
BOC Sciences Bioactive Compounds
Cayman Chemical Bioactives
ChEMBL Drugs
Drug Repurposing Hub
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
MedChem Express Bioactive Compound Library
NPC Screening Collection
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
Tool Compound Set
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
32
Molecular Weight
376.2
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
1
Rotatable Bonds
2
Ring Count
5
Aromatic Ring Count
2
cLogP
5.12
TPSA
46.53
Fraction CSP3
0.48
Chiral centers
5.0
Largest ring
6.0
QED
0.58
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Estrogen receptor alpha
Estrogen Receptor/ERR
hERα
mERα
ESR1
Bcl-2 Family
HBV
Estrogen/progestogen Receptor
MOA
contraceptive agent
Pathway
Anti-infection
Apoptosis
Vitamin D Related/Nuclear Receptor
Endocrinology/Hormones
Source data
