General
Preferred name
FLUDROCORTISONE ACETATE
Synonyms
9¦Á-Fludrocortisone acetate ()
9¦Á-Fluorcortisol acetate ()
9??-Fluorcortisol acetate ()
9??-Fludrocortisone acetate ()
9??-fluorocortisol acetate ()
9α-fluorocortisol acetate ()
9α-Fludrocortisone acetate ()
9α-Fluorcortisol acetate ()
dexamethasone acetate, Laboratoires CTRS ()
Astonin ()
Fluorhydrocortisone Acetate ()
Fludrocortisoni acetas ()
Panotile ()
Fludrocortisone 21-acetate ()
Fluorocortisol acetate ()
Florinef ()
Scherofluron ()
Fludrocortone ()
Fludrocortisona ()
NSC-15186 ()
P&D ID
PD012020
CAS
514-36-3
Tags
available
drug
prodrug
Approved by
FDA
First approval
1955
Drug Status
approved
Max Phase
4.0
Drug indication
Adrenocortical Steroid (salt-regulating)
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Compound Sets
12
Cayman Chemical Bioactives
24032
ChEMBL Approved Drugs
CHEMBL1201010
ChEMBL Drugs
CHEMBL1201010
Drug Repurposing Hub
DrugCentral
1191
DrugCentral Approved Drugs
1191
LSP-MoA library (Laboratory of Systems Pharmacology)
CHEMBL1201010
MedChem Express Bioactive Compound Library
HY-B1203A
NPC Screening Collection
ReFrame library
Selleckchem Bioactive Compound Library
fludrocortisone-acetate
TargetMol Bioactive Compound Library
T1666
External IDs
31
Properties
(calculated by RDKit )
Molecular Weight
422.21
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
2
Rotatable Bonds
3
Ring Count
4
Aromatic Ring Count
0
cLogP
2.44
TPSA
100.9
Fraction CSP3
0.78
Chiral centers
7.0
Largest ring
6.0
QED
0.68
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Autophagy
Endocrinology/Hormones
Metabolic Enzyme/Protease
Vitamin D Related/Nuclear Receptor
Target
Mineralocorticoid Receptor
NR3C2
MOA
Glucocorticoid Receptor
Indication
Addison's disease, adrenogenital syndrome
Source data