General
Preferred name
DESOXYCORTICOSTERONE ACETATE
Synonyms
Cortexone acetate ()
DOC acetate ()
11-Deoxycorticosterone acetate ()
Deoxycorticosterone acetate ()
Desoxycorticosterone acetate ()
11-Deoxycorticosterone acetate, DOC acetate, Cortexone acetate ()
NSC-9567 ()
NSC-11319 ()
Deoxycortone ()
DOCA ()
deoxycorticosterone ()
Desoxycortone acetate ()
DESOXYCORTICOSTERONE ()
11-deoxycorticosterone ()
desoxycortone ()
Percorten ()
21-hydroxyprogesterone ()
P&D ID
PD011996
CAS
56-47-3
106111-90-4
Tags
prodrug
natural product
drug
available
Approved by
FDA
First approval
1939
Drug Status
approved
withdrawn
Drug indication
Discovery agent
Adrenocortical Steroid (salt-regulating)
Max Phase
Phase 4
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Deoxycorticosterone acetate is a steroid hormone used for intramuscular injection for replacement therapy of the adrenocortical steroid.
(BOC Sciences Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
17
BOC Sciences Bioactive Compounds
Cayman Chemical Bioactives
ChEMBL Approved Drugs
ChEMBL Drugs
Drug Repurposing Hub
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
LSP-MoA library (Laboratory of Systems Pharmacology)
MedChem Express Bioactive Compound Library
NPC Screening Collection
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
Withdrawn 2.0
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
28
Molecular Weight
372.23
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
0
Rotatable Bonds
3
Ring Count
4
Aromatic Ring Count
0
cLogP
4.27
TPSA
60.44
Fraction CSP3
0.78
Chiral centers
6.0
Largest ring
6.0
QED
0.69
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Neuroscience
Metabolic Enzyme/Protease
Vitamin D Related/Nuclear Receptor
Target
Adrenergic Receptor
NR3C2
Endogenous Metabolite
Mineralocorticoid Receptor
MOA
progestogen hormone
ATC
H02AA03
Source data
