General
Preferred name
Eleutheroside E
Synonyms
P&D ID
PD011964
CAS
39432-56-9
Tags
available
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Eleutheroside E is an important component of ginseng that can be taken orally. Eleutheroside E has anti-inflammatory and antioxidant properties, and it helps reduce apoptosis in heart cells caused by hypoxia-reoxygenation (H/R) damage. Eleutheroside E can improve type 2 diabetes, enhance cognitive function, and has neuroprotective effects[1][2][3][4].
PRICE 74
DESCRIPTION Eleutheroside E has anti-inflammatory effects by inhibiting NF-??B activities. Eleutheroside E significantly decreases the inflammatory cell infiltration, pannus formation, cartilage damage, bone erosion of CIA mice, the generation of TNF-?? and IL-6, the metabolism of drugs metabolized via CYP2C9 and CYP2E1. Eleutheroside E may treat rheumatoid arthritis or increase the toxicity of the drugs.
DESCRIPTION Eleutheroside E has anti-inflammatory effects by inhibiting NF-κB activities. Eleutheroside E significantly decreases the inflammatory cell infiltration, pannus formation, cartilage damage, bone erosion of CIA mice, the generation of TNF-α and IL-6, the metabolism of drugs metabolized via CYP2C9 and CYP2E1. Eleutheroside E may treat rheumatoid arthritis or increase the toxicity of the drugs. (TargetMol Bioactive Compound Library)
Compound Sets
3
Cayman Chemical Bioactives
29684
MedChem Express Bioactive Compound Library
HY-N0272
TargetMol Bioactive Compound Library
T3662
External IDs
16
Properties
(calculated by RDKit )
Molecular Weight
742.27
Hydrogen Bond Acceptors
18
Hydrogen Bond Donors
8
Rotatable Bonds
12
Ring Count
6
Aromatic Ring Count
2
cLogP
-1.85
TPSA
254.14
Fraction CSP3
0.65
Chiral centers
14.0
Largest ring
6.0
QED
0.12
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
NF-κB
Apoptosis
Pathway
NF-¦ÊB
Source data