General
Preferred name
cholesterol
Synonyms
Cholesterol-d7 ()
NSC-8798 ()
Cholest-5-en-3-ol (3.beta.)- ()
Lidinit ()
Cholesterinum ()
Dythol ()
Cholesterol component of alf ()
Cholesterol component of alf43 ()
Cholesterol component of army liposome formulation ()
Provitamin-d ()
Lidinite ()
Cholesterol component of alfq ()
Cholesterol-d6 ()
Cholesterol (solution) ()
Cholesterol (plant) ()
Cholesterol-3,4-13C2 ()
P&D ID
PD011961
CAS
22243-67-0
209124-38-9
57-88-5
83199-47-7
60816-17-3
78887-48-6
Tags
available
drug
Drug indication
Discovery agent
Asperger syndrome
Drug Status
approved
investigational
Max Phase
2.0
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Cholesterol is a major sterol produced in mammalian cells that is required for cell viability and proliferation. Cholesterol plays an important role in determining the fluidity and permeability characteristics of the membrane as well as the function of both the transporters and signaling proteins. Cholesterol is also an endogenous estrogen-related receptor 1 (ERR1) agonist. (Enamine Bioactive Compounds)
Compound Sets
16
AdooQ Bioactive Compound Library
A22211
Cayman Chemical Bioactives
39088
39448
9003100
25265
25546
40278
ChEMBL Drugs
CHEMBL112570
Concise Guide to Pharmacology 2017/18
2718
Concise Guide to Pharmacology 2019/20
2718
Concise Guide to Pharmacology 2021/22
2718
Concise Guide to Pharmacology 2023/24
2718
Drug Repurposing Hub
DrugBank
DB04540
DrugBank Approved Drugs
DB04540
DrugMAP
DMR3J6S
Enamine Bioactive Compounds
EBC-03865
Enamine BioReference Compounds
Guide to Pharmacology
2718
MedChem Express Bioactive Compound Library
HY-N0322
NPC Screening Collection
External IDs
68
Properties
(calculated by RDKit )
Molecular Weight
386.35
Hydrogen Bond Acceptors
1
Hydrogen Bond Donors
1
Rotatable Bonds
5
Ring Count
4
Aromatic Ring Count
0
cLogP
7.39
TPSA
20.23
Fraction CSP3
0.93
Chiral centers
8.0
Largest ring
6.0
QED
0.49
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
RORA
Bacterial
Endogenous Metabolite
Estrogen Receptor/ERR
Liposome
Pathway
Anti-infection
Metabolic Enzyme/Protease
Vitamin D Related/Nuclear Receptor
Source data