General
Preferred name
NEOCUPROINE
Synonyms
Neocuproin ()
P&D ID
PD011780
CAS
303136-82-5
484-11-7
Tags
available
nuisance
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE 29
DESCRIPTION Neocuproine is a phenanthroline compound that is used as a chelating agent and copper ion detector. It also has inhibitory activity against Major prion protein with IC50 of 80 nM. (Enamine Bioactive Compounds)
DESCRIPTION Neocuproine is a copper(I) chelator that enhances the purinergic component of vasoconstriction induced by electric field stimulation, and is often used as a ligand reagent and copper ion detector.Neocuproine forms stable complexes with copper ions and can play a catalytic role in certain chemical reactions and analytical methods.Neocuproine acts as a redox-active on the iron and cobalt ligand platform for protection against oxidative damage in NSC34 cells. (TargetMol Bioactive Compound Library)
Cell lines
1
Organisms
2
Compound Sets
6
A Collection of Useful Nuisance Compounds (CONS) for Interrogation of Bioassay Integrity
Cayman Chemical Bioactives
20874
Enamine Bioactive Compounds
EBC-47351
NIH Mechanistic Set
Nuisance compounds in cellular assays
TargetMol Bioactive Compound Library
T33631
External IDs
29
Properties
(calculated by RDKit )
Molecular Weight
208.1
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
0
Rotatable Bonds
0
Ring Count
3
Aromatic Ring Count
3
cLogP
3.4
TPSA
25.78
Fraction CSP3
0.14
Chiral centers
0.0
Largest ring
6.0
QED
0.53
Structural alerts
1
Chelation
Fe
Nuisance compounds
Custom attributes
(extracted from source data)
Target
copper chelator
Nuisance MOA
Chelation
Targets
C-C chemokine receptor type 1
Source data