General
Preferred name
STREPTONIGRIN
Synonyms
Streptonigrin from Streptomyces flocculus ()
Bruneomycin ()
Rufocromomicina ()
NSC-45383 ()
Rufocromomycine ()
Nigrin ()
Rufocromomycin ()
NSC-83950 ()
P&D ID
PD011565
CAS
3930-19-6
Tags
drug candidate
nuisance
available
Drug indication
Discovery agent
Drug Status
investigational
Max Phase
2.0
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Cell lines
4
Organisms
1
Compound Sets
10
Cayman Chemical Bioactives
27952
ChEMBL Drugs
CHEMBL11417
DrugMAP
DM0HOEA
DrugMatrix
MedChem Express Bioactive Compound Library
HY-124586
NIH Mechanistic Set
NPC Screening Collection
Nuisance compounds in cellular assays
ReFrame library
ZINC Tool Compounds
ZINC000100016202
External IDs
29
Properties
(calculated by RDKit )
Molecular Weight
506.14
Hydrogen Bond Acceptors
11
Hydrogen Bond Donors
4
Rotatable Bonds
6
Ring Count
4
Aromatic Ring Count
3
cLogP
2.32
TPSA
197.18
Fraction CSP3
0.16
Chiral centers
0.0
Largest ring
6.0
QED
0.38
Structural alerts
2
quinone_A(370)
[!#6&!#1]=[#6]1[#6]=,:[#6][#6](=[!#6&!#1])[#6]=,:[#6]1
PAINS Family A
Redox
Redox cycling
Nuisance compounds
Custom attributes
(extracted from source data)
Target
antibiotic
Apoptosis
E1/E2/E3 Enzyme
HIF/HIF Prolyl-Hydroxylase
MDM-2/p53
Protein Arginine Deiminase
Pathway
Anti-infection
Epigenetics
Metabolic Enzyme/Protease
Source data