General
Preferred name
OXALIPLATIN
Synonyms
L-OHP ()
Oxaliplatin (Eloxatin) ()
P&D ID
PD011049
CAS
61825-94-3
Tags
available
drug
contains metal
Drug Status
approved
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE
31
DESCRIPTION
Oxaliplatin (L-OHP) is a DNA alkylating agent, an inhibitor of DNA synthesis. Oxaliplatin causes DNA cross-linking damage, preventing DNA replication and transcription and leading to cell death. Oxaliplatin induces autophagy.
(TargetMol Bioactive Compound Library)
DESCRIPTION
DNA cross-linking antitumor agent
(Tocris Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
4
AdooQ Bioactive Compound Library
NCATS Inxight Approved Drugs
TargetMol Bioactive Compound Library
Tocris Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
24
Molecular Weight
397.06
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
2
Rotatable Bonds
0
Ring Count
2
Aromatic Ring Count
0
cLogP
-0.79
TPSA
104.64
Fraction CSP3
0.75
Chiral centers
2.0
Largest ring
6.0
QED
0.52
QED
0.52
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Primary Target
Apoptosis Inducers
MOA
DNA/RNA Synthesis inhibitor
Pathway
Autophagy
Cell Cycle/Checkpoint
DNA Damage/DNA Repair
Target
DNA alkylator/crosslinker
DNA synthesis
DNA/RNA Synthesis
Source data
