General
Preferred name
Desfesoterodine
Synonyms
5-hydroxymethyl tolterodine ()
PNU-200577 ()
(R)-5-Hydroxymethyl tolterodine ()
5-hydroxymethyltolterodine ()
Spm 7605 ()
5-hydroxymethyl Tolterodine (formate) ()
P&D ID
PD010900
CAS
207679-81-0
380636-49-7
Tags
available
drug candidate
Drug Status
experimental
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
5-hydroxymethyl tolterodine produces a competitive and concentration-dependent inhibition of carbachol-induced contraction of guinea-pig isolated urinary bladder strips.
(BOC Sciences Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
7
AdooQ Bioactive Compound Library
BOC Sciences Bioactive Compounds
Cayman Chemical Bioactives
ChEMBL Drugs
Drug Repurposing Hub
DrugBank
MedChem Express Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
28
Molecular Weight
341.24
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
2
Rotatable Bonds
8
Ring Count
2
Aromatic Ring Count
2
cLogP
4.53
TPSA
43.7
Fraction CSP3
0.45
Chiral centers
1.0
Largest ring
6.0
QED
0.74
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
CHRM3
mAChR
MOA
acetylcholine receptor antagonist
Pathway
GPCR/G protein
Neuronal Signaling
Source data
