General
Preferred name
LY411575
Synonyms
LY-411575 ()
P&D ID
PD010875
CAS
209984-57-6
Tags
available
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Cell lines
0
Organisms
1
Compound Sets
7
AdooQ Bioactive Compound Library
A11176
Cayman Chemical Bioactives
16162
Drug Repurposing Hub
MedChem Express Bioactive Compound Library
HY-50752
Novartis Chemogenetic Library (NIBR MoA Box)
Selleckchem Bioactive Compound Library
ly-411575
TargetMol Bioactive Compound Library
T6063
External IDs
17
Properties
(calculated by RDKit )
Molecular Weight
479.17
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
3
Rotatable Bonds
5
Ring Count
4
Aromatic Ring Count
3
cLogP
3.0
TPSA
98.74
Fraction CSP3
0.19
Chiral centers
3.0
Largest ring
7.0
QED
0.52
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
¦Ã-secretase
Notch S3 cleavage
?? secretase (cell-based)
?? secretase (membrane-based)
??secretase
Notch
γ-secretase
Apoptosis related,Notch,Secretase
Pathway
Neuroscience
Proteases/Proteasome
Stem Cells
Apoptosis
Neuronal Signaling
Stem Cell/Wnt
Member status
member
MOA
gamma-Secretase Inhibitors
Antiamyloidogenic Agents
gamma secretase inhibitor
Source data