General
Preferred name
TERAZOSIN HYDROCHLORIDE
Synonyms
Flotrin dihydrate ()
Terazosin HCl Dihydrate ()
Dysalfa dihydrate ()
Heitrin dihydrate ()
Terazosin (hydrochloride dihydrate) ()
TERAZOSIN HYDROCHLORIDE DIHYDRATE ()
TERAZOSIN HYDROCHLORIDE ANHYDROUS ()
TERAZOSIN HCL 2H20 ()
BENPH ()
Terazosin HCl ()
ITRIN ()
ABBOTT-45975 ANHYDROUS ()
HYTRACIN ()
HEITRIN ()
TERAZOSIN (AS HYDROCHLORIDE) ()
Hytrin ()
ABBOTT-45975 ()
HYTRIN BPH ()
NSC-759168 ()
TERAZOSIN HYDROCHLORIDE HYDRATE ()
URODIE ()
Tezruly ()
TERAZOSIN ()
TEZRULY ()
P&D ID
PD010871
CAS
70024-40-7
Tags
available
drug
Drug Status
approved
Max Phase
4.0
Drug indication
Benign prostatic hyperplasia
First approval
1987
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE
29
DESCRIPTION
Terazosin hydrochloride dihydrate is a quinazoline derivative and a competitive and orally active ¦Á1-adrenoceptor antagonist. Terazosin hydrochloride dihydrate works by relaxing blood vessels and the opening of the bladder. Terazosin hydrochloride dihydrate has the potential for benign prostatic hyperplasia (BPH) and high blood pressure treatment[1][2][3].
DESCRIPTION
Terazosin hydrochloride dihydrate (Heitrin dihydrate) is a selective ??1-adrenoceptor antagonist, used for treatment of symptoms of an enlarged prostate (BPH).
DESCRIPTION
Terazosin hydrochloride dihydrate (Heitrin dihydrate) is a selective α1-adrenoceptor antagonist, used for treatment of symptoms of an enlarged prostate (BPH).
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
6
ChEMBL Approved Drugs
ChEMBL Drugs
EUbOPEN Chemogenomics Library
MedChem Express Bioactive Compound Library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
17
Molecular Weight
459.19
Hydrogen Bond Acceptors
8
Hydrogen Bond Donors
1
Rotatable Bonds
4
Ring Count
4
Aromatic Ring Count
2
cLogP
-0.17
TPSA
166.04
Fraction CSP3
0.53
Chiral centers
1.0
Largest ring
6.0
QED
0.66
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Adrenergic Receptor
α1-adrenoceptor
Pathway
GPCR/G protein
Neuroscience
Neuronal Signaling
Recommended Cell Concentration
None
Source data
