General
Preferred name
LUTEOLIN
Synonyms
ML061 Analog ()
Digitoflavone ()
Luteoline ()
Luteolol ()
Flacitran ()
B-Lactams ()
Flavonoid derivative 1 ()
Luteoline, Luteolol, Digitoflavone ()
Cyanidenon-1470 ()
Weld lake ()
Yama kariyasu ()
Salifazide ()
P&D ID
PD010790
CAS
491-70-3
Tags
obsolete probe
nuisance
probe
drug
natural product
available
Drug indication
Bacterial infection
Drug Status
experimental
investigational
approved
Max Phase
Phase 2
Probe info
Probe selectivity
protein-selective
Probe type
calculated probe
Probe sources
Probe targets
[[ compound.targets[t].gene_name ]]
Probe control
Probe control not defined
Orthogonal probes
1
No orthogonal probes found
Similar probes
1
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Luteolin is a flavone, a type of flavonoid, naturally occuring in a variety of plants. It has antimalarial activity, inhibiting the growth of P. falciparum during the intraerythrocytic stages of the parasite's lifecycle .
(GtoPdb)
DESCRIPTION
5-HT and NA reuptake inhibitor (SNRI)
(Tocris Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
18
Organisms
7
Compound Sets
20
AdooQ Bioactive Compound Library
Cayman Chemical Bioactives
ChEMBL Drugs
Concise Guide to Pharmacology 2023/24
Drug Repurposing Hub
DrugBank
DrugMAP Approved Drugs
Guide to Pharmacology
IPPI - DB
MedChem Express Bioactive Compound Library
MLSMR Probes +
Nuisance compounds in cellular assays
Obsolete Compounds
Prestwick Chemical Library
Probe Miner (suitable probes)
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
Tocris Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
41
Molecular Weight
286.05
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
4
Rotatable Bonds
1
Ring Count
3
Aromatic Ring Count
3
cLogP
2.28
TPSA
111.13
Fraction CSP3
0.0
Chiral centers
0.0
Largest ring
6.0
QED
0.51
Structural alerts
4
aggregator (Aggregator Advisor)
Aggregators
historic compounds (Chemical Probes.org)
Obsolete
aggregator (ZINC)
Aggregators
Nonspecific/NOS
Flavonoid
Nuisance compounds in cellular assays
Related compounds
Custom attributes
(extracted from source data)
Classification
probe analog
Pathway
Metabolism
Apoptosis
Autophagy
Metabolic Enzyme/Protease
NF-κB
Target
PDE1
PDE2
PDE3
PDE4
PDE5
TOP1
Endogenous Metabolite
Keap1-Nrf2
ADC Cytotoxin,PDE
Primary Target
Antioxidants
MOA
glucosidase inhibitor
Source data
