General
Preferred name
OSTHOLE
Synonyms
Osthol ()
Ostol ()
NSC 31868 ()
P&D ID
PD010781
CAS
484-12-8
1440642-68-1
Tags
natural product
available
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Osthole is a bioactive natural botanical compound with anti-fungal and antipruritic activities. It is a reported TRPV3 channel blocker . (GtoPdb)
Cell lines
9
Organisms
0
Compound Sets
12
AdooQ Bioactive Compound Library
A10680
Cayman Chemical Bioactives
19195
Concise Guide to Pharmacology 2019/20
10302
Concise Guide to Pharmacology 2021/22
10302
Concise Guide to Pharmacology 2023/24
10302
Drug Repurposing Hub
Guide to Pharmacology
10302
Mcule NIBR MoA Box Subset
MCULE-5691054147
MedChem Express Bioactive Compound Library
HY-N0054
Novartis Chemogenetic Library (NIBR MoA Box)
Selleckchem Bioactive Compound Library
Osthole(Osthol)
TargetMol Bioactive Compound Library
T2848
External IDs
32
Properties
(calculated by RDKit )
Molecular Weight
244.11
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
0
Rotatable Bonds
3
Ring Count
2
Aromatic Ring Count
2
cLogP
3.31
TPSA
39.44
Fraction CSP3
0.27
Chiral centers
0.0
Largest ring
6.0
QED
0.61
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
GPCR/G protein
Immunology/Inflammation
Neuroscience
Anti-infection
Apoptosis
Neuronal Signaling
Target
H1 receptor
HBV
Histamine Receptor
Parasite
Member status
member
MOA
ACAT Inhibitors
calcium channel blocker
Source data