General
Preferred name
DIOSMETIN
Synonyms
Luteolin 4-methyl ether ()
Flavonoid derivative 3 ()
Diosmetine ()
Diosmetin-d3 ()
P&D ID
PD010735
CAS
520-34-3
1189728-54-8
Tags
natural product
drug
available
Approved by
FDA
Drug indication
Discovery agent
Drug Status
experimental
approved
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
5
Organisms
0
Compound Sets
11
AdooQ Bioactive Compound Library
Drug Repurposing Hub
DrugBank
DrugCentral
DrugCentral Approved Drugs
EU-OPENSCREEN Bioactive Compound Library
MedChem Express Bioactive Compound Library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
40
Properties
(calculated by RDKit )
Molecular Weight
300.06
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
3
Rotatable Bonds
2
Ring Count
3
Aromatic Ring Count
3
cLogP
2.59
TPSA
100.13
Fraction CSP3
0.06
Chiral centers
0.0
Largest ring
6.0
QED
0.67
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Metabolism
Tyrosine Kinase/Adaptors
Metabolic Enzyme/Protease
Target
CYP1A1
TrkB
CYP1B1
Cytochrome P450
P450 (e.g. CYP17)
Indication
cosmetic
MOA
aryl hydrocarbon receptor agonist
Source data
