General
Preferred name
NVP-BGT226
Synonyms
BGT226 maleate ()
NVP-BGT226 (maleate) ()
BGT226 ()
NVP-BGT226 (maleate)NVP-BGT226 ()
BGT226 (maleate) ()
BGT-226 ()
BGT226 (NVP-BGT226) maleate ()
NVP-BGT-226 ()
NVP-BGT226 ()
P&D ID
PD010685
CAS
1245537-68-1
915020-55-2
Tags
available
drug candidate
Drug Status
investigational
Max Phase
Phase 2
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
7
AdooQ Bioactive Compound Library
Axon Medchem Screening Library
Cayman Chemical Bioactives
ChEMBL Drugs
MedChem Express Bioactive Compound Library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
11
Properties
(calculated by RDKit )
Molecular Weight
650.21
Hydrogen Bond Acceptors
10
Hydrogen Bond Donors
3
Rotatable Bonds
6
Ring Count
6
Aromatic Ring Count
5
cLogP
4.09
TPSA
151.81
Fraction CSP3
0.22
Chiral centers
0.0
Largest ring
6.0
QED
0.23
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
PI3K/Akt/mTOR signaling
Apoptosis
Autophagy
PI3K/Akt/mTOR
Target
PI3K??
PI3K/mTOR inhibitor
MTOR
PI3K
mTOR,PI3K
Source data
