General
Preferred name
TEMPOL
Synonyms
TMPN ()
Tanol ()
4-Hydroxy-TEMPO ()
MBM-02 ()
ZJ-701 ()
SPJ-701 ()
NSC-142784 ()
4-oxypiperidol ()
P&D ID
PD010519
CAS
2226-96-2
105269-77-0
3637-10-3
Tags
available
drug candidate
Drug indication
Spinal cord injury
Cardiovascular disease
Drug Status
investigational
Max Phase
2.0
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE 29
DESCRIPTION Tempol is a superoxide scavenger that displays neuroprotective, anti-inflammatory and analgesic effects. (BOC Sciences Bioactive Compounds)
DESCRIPTION Tempol (Tanol) is a superoxide scavenger. It has anti-inflammatory, neuroprotective and analgesic effects. (TargetMol Bioactive Compound Library)
DESCRIPTION Na+/2Cl-/K+ (NKCC) symporter inhibitor (Tocris Bioactive Compound Library)
Compound Sets
11
AdooQ Bioactive Compound Library
A13157
BOC Sciences Bioactive Compounds
tempol-cas-2226-96-2-333288
Cayman Chemical Bioactives
27051
ChEMBL Drugs
CHEMBL607023
DrugBank
DB12449
DrugMAP
DMUQH78
MedChem Express Bioactive Compound Library
HY-100561
ReFrame library
Selleckchem Bioactive Compound Library
tempol-4-hydroxy-tempo
TargetMol Bioactive Compound Library
T6699
Tocris Bioactive Compound Library
3082
External IDs
30
Properties
(calculated by RDKit )
Molecular Weight
172.13
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
1
Rotatable Bonds
0
Ring Count
1
Aromatic Ring Count
0
cLogP
1.35
TPSA
43.37
Fraction CSP3
1.0
Chiral centers
0.0
Largest ring
6.0
QED
0.6
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Pathway
Autophagy
Immunology/Inflammation
Metabolism
NF-κB
Metabolic Enzyme/Protease
Primary Target
Antioxidants
Solubility
Soluble in Methanol
Target
Immunology & Inflammation related
Reactive Oxygen Species (ROS)
Reactive Oxygen Species
ROS
Source data