General
Preferred name
pifithrin-alpha
Synonyms
Pifithrin- α hydrobromide ()
Pifithrin-¦Á (hydrobromide) ()
PFT¦Á hydrobromide ()
PFT?? hydrobromide ()
Pifithrin hydrobromide ()
Pifithrin-?? hydrobromide ()
Pifithrin-?? (PFT??) HBr ()
PFT?? ()
Pifithrin-?? ()
Pifithrin-α (PFTα) HBr ()
Pifithrin-alpha hydrobromide ()
PFT¦Á ()
Pifithrin-?? (hydrobromide) ()
Pifithrin-a hydrobromide ()
Pifithrin-α (hydrobromide) ()
PFTα hydrobromide ()
Pifithrin-¦Á (PFT¦Á) HBr ()
Pifithrin-¦Á hydrobromide ()
Pifithrin-.alpha. ()
P&D ID
PD010509
CAS
63208-82-2
206983-57-5
Tags
available
obsolete probe
drug candidate
Drug indication
Toxicity
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Inhibitor of tubulin (Tocris Bioactive Compound Library)
DESCRIPTION p53 inhibitor. Also aryl hydrocarbon receptor agonist (Tocriscreen Total)
Cell lines
0
Organisms
1
Compound Sets
10
AdooQ Bioactive Compound Library
A12451
Axon Medchem Screening Library
1871
Cayman Chemical Bioactives
13326
DrugMAP
DM63OD7
MedChem Express Bioactive Compound Library
HY-15484
Obsolete Compounds
pifithrin-alpha
Selleckchem Bioactive Compound Library
pifithrin-alpha
TargetMol Bioactive Compound Library
T2707
Tocris Bioactive Compound Library
1267
Tocriscreen Total
External IDs
21
Properties
(calculated by RDKit )
Molecular Weight
366.04
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
1
Rotatable Bonds
3
Ring Count
3
Aromatic Ring Count
2
cLogP
3.68
TPSA
45.85
Fraction CSP3
0.38
Chiral centers
0.0
Largest ring
6.0
QED
0.83
Structural alerts
1
historic compounds (Chemical Probes.org)
Obsolete
Related compounds
Custom attributes
(extracted from source data)
Pathway
Apoptosis
Immunology/Inflammation
Target
p53
p53 inhibitor
Aryl hydrocarbon receptor
Ferroptosis
MDM-2/p53
AhR,Autophagy,p53
MOA
Inhibitor
Source data