General
Preferred name
AZILSARTAN
Synonyms
TAK-536 ()
Azilsartan D5 ()
TAK-536 D5 ()
Azilsartan (TAK-536) ()
Azilsartan-d5 ()
P&D ID
PD010495
CAS
147403-03-0
1346599-45-8
Tags
natural product
drug
available
Drug indication
Hypertension
Drug Status
investigational
approved
Max Phase
Phase 3
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
The active form of the approved drug azilsartan medoxomil.
(GtoPdb)
DESCRIPTION
Potent and selective CGRP antagonist
(Tocris Bioactive Compound Library)
DESCRIPTION
Potent AT1 receptor inverse agonist; antihypertensive
(Tocriscreen Plus)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
18
AdooQ Bioactive Compound Library
Axon Medchem Screening Library
ChEMBL Drugs
Concise Guide to Pharmacology 2017/18
Drug Repurposing Hub
DrugMAP
DrugMAP Approved Drugs
DrugMatrix
Enamine BioReference Compounds
Guide to Pharmacology
MedChem Express Bioactive Compound Library
NCATS Inxight Approved Drugs
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
Tocris Bioactive Compound Library
Tocriscreen Plus
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
38
Molecular Weight
456.14
Hydrogen Bond Acceptors
7
Hydrogen Bond Donors
2
Rotatable Bonds
7
Ring Count
5
Aromatic Ring Count
5
cLogP
4.19
TPSA
123.24
Fraction CSP3
0.12
Chiral centers
0.0
Largest ring
6.0
QED
0.38
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target Type
7-TM Receptors
Target
Angiotensin Receptor
AT1 receptor
AGTR1, AGTR2
AT1 antagonist
Reactive Oxygen Species
Pathway
GPCR/G protein
Endocrinology/Hormones
Apoptosis
Immunology/Inflammation
Metabolic Enzyme/Protease
NF-κB
Primary Target
Angiotensin AT1 Receptors
MOA
Inverse Agonist
angiotensin receptor antagonist
Indication
hypertension
Source data
