General
Preferred name
HYDROXYZINE HYDROCHLORIDE
Synonyms
Hydroxyzine 2HCl ()
Hydroxyzine dihydrochloride ()
Hydroxyzine (dihydrochloride) ()
Hydroxizine Chloride ()
Atarax ()
Ucerax ()
Vistaril ()
HYDROXYZINE ()
Orgatrax ()
P&D ID
PD010482
CAS
2192-20-3
Tags
natural product
drug
available
Drug Status
approved
Max Phase
Phase 4
First approval
1956
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
8
ChEMBL Approved Drugs
ChEMBL Drugs
Enamine BioReference Compounds
MedChem Express Bioactive Compound Library
Prestwick Chemical Library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
The Spectrum Collection
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
20
Properties
(calculated by RDKit )
Molecular Weight
446.13
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
1
Rotatable Bonds
8
Ring Count
3
Aromatic Ring Count
2
cLogP
3.9
TPSA
35.94
Fraction CSP3
0.43
Chiral centers
1.0
Largest ring
6.0
QED
0.62
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
GPCR/G protein
Immunology/Inflammation
Neuroscience
Neuronal Signaling
Target
H1 receptor
Histamine Receptor
Source data
