General
Preferred name
ABT-418
Synonyms
ABT-418 hydrochloride ()
ABT-418 (hydrochloride) ()
P&D ID
PD010436
CAS
147402-53-7
147388-83-8
Tags
available
drug candidate
Drug indication
Alzheimer disease
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Neuronal nicotinic acetylcholine receptor agonist with cognition enhancing and anxiolytic activities
(LOPAC library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
1
Organisms
1
Compound Sets
4
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
27
Molecular Weight
166.11
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
0
Rotatable Bonds
1
Ring Count
2
Aromatic Ring Count
1
cLogP
1.75
TPSA
29.27
Fraction CSP3
0.67
Chiral centers
1.0
Largest ring
5.0
QED
0.64
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Selectivity
Nicotinic
Pathway
Membrane Transporter/Ion Channel
Neuronal Signaling
Target
nAChR
Source data
