General
Preferred name
UNC 669
Synonyms
UNC669 ()
UNC-669 ()
P&D ID
PD010329
CAS
1314241-44-5
Tags
available
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION UNC 669, a ligand for a methyl-lysine binding domain, is a potent L3MBTL1 (IC50=4.2 uM) and L3MBTL3 (3.1 uM) inhibitor[1].
PRICE 29
DESCRIPTION (5-Bromopyridin-3-yl)(4-(pyrrolidin-1-yl)piperidin-1-yl)methanone is a selective inhibitor of malignant brain tumor (MBT). (BOC Sciences Bioactive Compounds)
DESCRIPTION UNC 669 is an effective and specific MBT (malignant brain tumor) inhibitor with IC50 of 4.2/3.1 uM for L3MBTL1/3. (TargetMol Bioactive Compound Library)
Compound Sets
9
Axon Medchem Screening Library
2163
BOC Sciences Bioactive Compounds
unc-669-cas-1314241-44-5-item-84-463173
Cayman Chemical Bioactives
10875
CZ-OPENSCREEN Bioactive Library
Drug Repurposing Hub
LINCS compound set
10333-101
MedChem Express Bioactive Compound Library
HY-15839
Selleckchem Bioactive Compound Library
unc669
TargetMol Bioactive Compound Library
T2252
External IDs
14
Properties
(calculated by RDKit )
Molecular Weight
337.08
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
0
Rotatable Bonds
2
Ring Count
3
Aromatic Ring Count
1
cLogP
2.54
TPSA
36.44
Fraction CSP3
0.6
Chiral centers
0.0
Largest ring
6.0
QED
0.83
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Epigenetic Reader Domain
L3MBTL1
L3MBTL3
L3MBTL4
L3MBTL inhibitor
MOA
L3MBTL antagonist
Pathway
Epigenetics
Chromatin/Epigenetic
Source data