General
Preferred name
CETRORELIX
Synonyms
NS-75A diacetate ()
SB-075 diacetate ()
Cetrorelix diacetate ()
Cetrorelix (acetate) ()
CETRORELIX ACETATE ()
SB-75 (acetate) ()
Ac-3-(2-naphthyl)-D-Ala-4-Chloro-D-Phe-3(3-pyridyl)-D-Ala-Ser-Tyr-D-Cit-Leu-Arg-Pro-D-Ala-NH2 ()
Cetrotide ()
Cetrorelix ()
NS-75A ()
Cetrotide acetate ()
SB-075 acetate ()
D-20761 ()
P&D ID
PD010240
CAS
130143-01-0
120287-85-6
145672-81-7
Tags
available
drug
Approved by
PMDA
EMA
FDA
First approval
2000
1999
Drug Status
investigational
approved
Drug indication
Ovarian stimulation
Max Phase
Phase 4
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Cetrorelix is a synthetic GnRH receptor antagonist. Natural GnRH is a decapeptide hormone.
(GtoPdb)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
15
ChEMBL Approved Drugs
ChEMBL Drugs
Drug Repurposing Hub
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
Guide to Pharmacology
MedChem Express Bioactive Compound Library
NCATS Inxight Approved Drugs
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
65
Molecular Weight
1429.67
Hydrogen Bond Acceptors
16
Hydrogen Bond Donors
17
Rotatable Bonds
38
Ring Count
6
Aromatic Ring Count
5
cLogP
-0.51
TPSA
495.67
Fraction CSP3
0.43
Chiral centers
10.0
Largest ring
6.0
QED
0.01
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
GPCR/G protein
Target
GNRHR
GNRHR, LHCGR
GNRH Receptor
Indication
premature luteinizing hormone surges
MOA
gonadotropin releasing factor hormone receptor antagonist
Therapeutic Class
Infertility Agents
Source data
