General
Preferred name
S-adenosyl methionine
Synonyms
S-Adenosyl-L-methionine disulfate tosylate ()
SAMe ()
S-(5'-Adenosyl)-L-methionine p-toluenesulfonate salt ()
Ademetionine disulfate tosylate ()
S-(5'-Adenosyl)-L-methionine tosylate ()
S-Adenosyl-L-methionine (tosylate) ()
S-Adenosyl-L-methionine (disulfate tosylate) ()
S-Adenosyl methionine (tosylate) ()
Ademetionine (tosylate) ()
AdoMet (tosylate) ()
Ademetionine (disulfate tosylate) ()
S-Adenosyl methionine (disulfate tosylate) ()
AdoMet (disulfate tosylate) ()
S-(5'-Adenosyl)-L-methionine (tosylate) ()
S-(5’-Adenosyl)-L-methionine (sulfate tosylate) ()
P&D ID
PD010234
CAS
97540-22-2
52248-03-0
Tags
natural product
available
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
This compound is sold as a nutritional supplement in the US and Canada and is approved as a prescription drug in some EU countries (approval date not available), where it is used to treat depression, liver disorders, fibromyalia and osteoarthritis.
(GtoPdb)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
12
AdooQ Bioactive Compound Library
Concise Guide to Pharmacology 2017/18
Concise Guide to Pharmacology 2019/20
Concise Guide to Pharmacology 2021/22
Concise Guide to Pharmacology 2023/24
Drug Repurposing Hub
EU-OPENSCREEN Bioactive Compound Library
Guide to Pharmacology
MedChem Express Bioactive Compound Library
Selleckchem Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
57
Molecular Weight
399.14
Hydrogen Bond Acceptors
10
Hydrogen Bond Donors
5
Rotatable Bonds
7
Ring Count
3
Aromatic Ring Count
2
cLogP
-1.92
TPSA
182.63
Fraction CSP3
0.6
Chiral centers
6.0
Largest ring
6.0
QED
0.33
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
APE1(Ref-1)
Endogenous Metabolite
Anti-infection
Indication
depression, attention-deficit/hyperactivity disorder (ADHD)
MOA
methyltransferase stimulant, phosphodiesterase inhibitor
Pathway
Apoptosis
Metabolic Enzyme/Protease
Source data
