General
Preferred name
ASCORBIC ACID
Synonyms
Vitamin C ()
L(+)-Ascorbic acid ()
L-Ascorbate ()
L-ascorbic acid ()
[14C]ascorbic acid ()
NSC-33832 ()
Vitamin c (as ascorbic acid) ()
E-300 ()
Ascor ()
Redoxon ()
NSC-218455 ()
3-keto-l-gulofuranolactone ()
E300 ()
INS NO.300 ()
FEMA NO. 2109 ()
Redoxon C ()
Top C ()
Vital Life ()
Ascorbic acid component of vitaped ()
Ascoltin ()
Ascorbicum acidum ()
Bassett's ()
Haliborange ()
Acido ascorbico ()
Ascur ()
Redoxon Slow Release ()
Acidum ascorbicum ()
Ascorbicap ()
Ascorbic acid (vit c) ()
INS-300 ()
Ascorbic acid component of plenvu ()
Ascorbic acid component of moviprep ()
Acide ascorbique ()
Ascorbic acid, l- ()
Redoxon Chew-C ()
ASCORBATE ()
Ascorbic Acid ()
P&D ID
PD010229
CAS
50-81-7
Tags
available
probe
drug
nuisance
Approved by
FDA
Drug indication
Vitamin C deficiency
Urinary tract infection
Iron deficiency anemia
Drug Status
approved
nutraceutical
Max Phase
4.0
First approval
1985
Probe info
Probe type
P&D approved
calculated probe
Probe selectivity
protein-selective
Probe sources
Probe targets
[[ compound.targets[t].gene_name ]]
Probe control
Probe control not defined
Orthogonal probes
1
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCPRITION
A six carbon compound related to glucose. It is found naturally in citrus fruits and many vegetables. Ascorbic acid is an essential nutrient in human diets, and necessary to maintain connective tissue and bone. Its biologically active form, vitamin C, functions as a reducing agent and coenzyme in several metabolic pathways. Vitamin C is considered an antioxidant.
DESCRIPTION
L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 ¦ÌM. L-Ascorbic acid is also a collagen deposition enhancer and an elastogenesis inhibitor[1][2][3]. L-Ascorbic acid exhibits anti-cancer effects through the generation of reactive oxygen species (ROS) and selective damage to cancer cells[4].
PRICE
29
DESCRIPTION
L-Ascorbic acid (Vitamin C) is a natural product that is a potent reducing agent and antioxidant. L-Ascorbic acid functions in fighting bacterial infections, in detoxifying reactions, and in the formation of collagen. L-Ascorbic acid is used in the treatment of scurvy.
(TargetMol Bioactive Compound Library)
DESCRIPTION
Microtubule stabilizer
(Tocris Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
1
Organisms
0
Compound Sets
25
A Collection of Useful Nuisance Compounds (CONS) for Interrogation of Bioassay Integrity
Cayman Chemical Bioactives
ChEMBL Approved Drugs
ChEMBL Drugs
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
High-quality chemical probes
MedChem Express Bioactive Compound Library
NCATS Inxight Approved Drugs
NPC Screening Collection
Nuisance compounds in cellular assays
Prestwick Chemical Library
Probe Miner (suitable probes)
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
Tocris Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
65
Molecular Weight
176.03
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
4
Rotatable Bonds
2
Ring Count
1
Aromatic Ring Count
0
cLogP
-1.41
TPSA
107.22
Fraction CSP3
0.5
Chiral centers
2.0
Largest ring
5.0
QED
0.39
Structural alerts
1
Singlet oxygen quenching
Nuisance compounds
Related compounds
Custom attributes
(extracted from source data)
Pathway
NF-¦ÊB
Immunology/Inflammation
Membrane Transporter/Ion Channel
Metabolism
NF-κB
Metabolic Enzyme/Protease
Neuronal Signaling
Target
Apoptosis
Calcium Channel
Endogenous Metabolite
Reactive Oxygen Species
VC
Reactive Oxygen Species (ROS)
Vitamin
Primary Target
Stem Cell Reprogramming
Therapeutic Class
Vitamins
Nuisance MOA
Singlet oxygen quenching
Targets
Antioxidant agent
Source data
