General
Preferred name
ASCORBIC ACID
Synonyms
Vitamin C ()
L-Ascorbate ()
L-ascorbic acid ()
L(+)-Ascorbic acid ()
E300 ()
Ascorbicum acidum ()
Top C ()
ASCORBATE ()
E-300 ()
Ascor ()
Ascorbic acid, l- ()
Ascoltin ()
Haliborange ()
3-keto-l-gulofuranolactone ()
INS NO.300 ()
FEMA NO. 2109 ()
Redoxon ()
NSC-33832 ()
Acidum ascorbicum ()
Redoxon Slow Release ()
Cenolate ()
Acido ascorbico ()
Redoxon Chew-C ()
Bassett's ()
Cevitamic Acid ()
Redoxon C ()
Vital Life ()
Ascorbic acid (vit c) ()
Acide ascorbique ()
NSC-218455 ()
Vitamin c (as ascorbic acid) ()
Ascur ()
INS-300 ()
Cecon ()
Ascorbic Acid ()
P&D ID
PD010229
CAS
50-81-7
Tags
available
nuisance
drug
probe
Approved by
FDA
Drug indication
Vitamin C deficiency
Urinary tract infection
Acidifier (urlnary)
Vitamin (antiscorbutic)
Drug Status
approved
nutraceutical
Max Phase
4.0
First approval
1985
Probe info
Probe selectivity
protein-selective
Probe type
P&D approved
calculated probe
Probe sources
High-quality chemical probes
Probe Miner (suitable probes)
Probe targets
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCPRITION A six carbon compound related to glucose. It is found naturally in citrus fruits and many vegetables. Ascorbic acid is an essential nutrient in human diets, and necessary to maintain connective tissue and bone. Its biologically active form, vitamin C, functions as a reducing agent and coenzyme in several metabolic pathways. Vitamin C is considered an antioxidant.
DESCRIPTION Used as a nutritional supplement to treat vitamin C deficiency (scurvy) and to help promote wound and bone healing. (GtoPdb)
DESCRIPTION Microtubule stabilizer (Tocris Bioactive Compound Library)
Cell lines
1
Organisms
0
Compound Sets
25
A Collection of Useful Nuisance Compounds (CONS) for Interrogation of Bioassay Integrity
Cayman Chemical Bioactives
14656
ChEMBL Approved Drugs
CHEMBL196
ChEMBL Drugs
CHEMBL196
Concise Guide to Pharmacology 2017/18
4781
4532
Concise Guide to Pharmacology 2019/20
4781
4532
Concise Guide to Pharmacology 2021/22
4781
4532
Concise Guide to Pharmacology 2023/24
4781
4532
DrugBank
DB00126
DrugBank Approved Drugs
DB00126
DrugCentral
4072
DrugCentral Approved Drugs
4072
DrugMAP
DMXJ7O8
DrugMAP Approved Drugs
DMXJ7O8
Guide to Pharmacology
4781
4532
High-quality chemical probes
PD010229
MedChem Express Bioactive Compound Library
HY-B0166
NCATS Inxight Approved Drugs
PQ6CK8PD0R
NPC Screening Collection
Nuisance compounds in cellular assays
Prestwick Chemical Library
Probe Miner (suitable probes)
P18089/8818
Selleckchem Bioactive Compound Library
vitamin-c-ascorbic-acid
TargetMol Bioactive Compound Library
T0928
Tocris Bioactive Compound Library
4055
External IDs
65
Properties
(calculated by RDKit )
Molecular Weight
176.03
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
4
Rotatable Bonds
2
Ring Count
1
Aromatic Ring Count
0
cLogP
-1.41
TPSA
107.22
Fraction CSP3
0.5
Chiral centers
2.0
Largest ring
5.0
QED
0.39
Structural alerts
1
Singlet oxygen quenching
Nuisance compounds
Related compounds
Custom attributes
(extracted from source data)
Pathway
NF-¦ÊB
Metabolism
Apoptosis
Immunology/Inflammation
Membrane Transporter/Ion Channel
Metabolic Enzyme/Protease
Neuronal Signaling
NF-κB
Target
VC
Calcium Channel
Endogenous Metabolite
Reactive Oxygen Species
Vitamin
Primary Target
Stem Cell Reprogramming
Therapeutic Class
Vitamins
Nuisance MOA
Singlet oxygen quenching
Targets
Antioxidant agent
Source data