General
Preferred name
ORNITHINE
Synonyms
(S)-2,5-Diaminopentanoic acid ()
L(+)-Ornithine hydrochloride ()
L-Ornithine-α-ketoglutarate ()
Ornithine α ketoglutarate ()
L Ornithine α ketoglutarate ()
Ornithine α-ketoglutarate ()
OKG ()
Ornithine Aspartate ()
L-Ornithine Hydrochloride(S)-2,5-Diaminopentanoic acid ()
L-Ornithine hydrochloride ()
L-ornithine phenylacetate ()
L-ornithine ()
L-Ornithine 2-oxoglutarate ()
L-Ornithine (hydrochloride) ()
Ornithine-α-ketoglutarate ()
L-Ornithine L-aspartate ()
ORNITHINE OXOGLURATE ()
Ornithine phenylacetate ()
NSC-758894 ()
Ornitina ()
Ornithine, (l)-isomer ()
.alpha.-ketoglutaric acid compound with l(+)-ornithine ()
Ornithine monoxoglurate ()
Ornicetil ()
Ornithine .alpha.-ketoglutarate ()
Cetornan ()
Ornithine oxoglutarate ()
OCR-002 ()
L-OP ()
L-ornithine, benzeneacetate (1:1) ()
OP ()
Ornithine-??-ketoglutarate ()
P&D ID
PD010228
CAS
3054-39-5
410523-46-5
25104-12-5
34414-83-0
5191-97-9
33024-89-4
16682-12-5
952154-79-9
3184-13-2
70-26-8
3230-94-2
Tags
available
drug
drug candidate
Drug indication
Acute liver failure
Discovery agent
Neuroblastoma
cirrhosis of liver
Drug Status
approved
investigational
nutraceutical
Max Phase
2.0
3.0
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE 29
PRICE 30
DESCRIPTION Ornithine-??-ketoglutarate (L-Ornithine-??-ketoglutarate) is a salt formed of 2 molecules of ornithine and 1 alpha-ketoglutarate. Ornithine-??-ketoglutarate improves nutritional status in chronically malnourished (e.g., elderly) and acutely malnourished patients (especially burn and trau
PRICE 29
PRICE 29
DESCRIPTION L-Ornithine ((S)-2,5-Diaminopentanoic acid) exhibits an anti-fatigue function by promoting ammonia excretion and enhancing energy consumption efficiency. (TargetMol Bioactive Compound Library)
DESCRIPTION Ornithine-α-ketoglutarate (L-Ornithine-α-ketoglutarate) is a salt formed of 2 molecules of ornithine and 1 alpha-ketoglutarate. Ornithine-α-ketoglutarate improves nutritional status in chronically malnourished (e.g., elderly) and acutely malnourished patients (especially burn and trau (TargetMol Bioactive Compound Library)
DESCRIPTION L-ornithine hydrochloride has an antifatigue effect by increasing the efficiency of energy consumption and promoting the excretion of ammonia. It is one of the key reactants in the urea cycle. (Enamine Bioactive Compounds)
DESCRIPTION L-Ornithine hydrochloride ((S)-2,5-Diaminopentanoic acid) has an antifatigue effect by increasing the efficiency of energy consumption and promoting the excretion of ammonia. It is one of the key reactants in the urea cycle. (TargetMol Bioactive Compound Library)
DESCRIPTION L-Ornithine L-aspartate (Ornithine Aspartate) lowers blood ammonia concentration and to eliminate symptoms of hepatic encephalopathy associated with liver cirrhosis. (TargetMol Bioactive Compound Library)
Compound Sets
19
Cayman Chemical Bioactives
30779
ChEMBL Drugs
CHEMBL446143
CHEMBL3138616
CHEMBL4297204
Concise Guide to Pharmacology 2017/18
725
Concise Guide to Pharmacology 2019/20
725
Concise Guide to Pharmacology 2021/22
725
Concise Guide to Pharmacology 2023/24
725
DrugBank
DB00129
DrugBank Approved Drugs
DB00129
DrugCentral
3401
DrugCentral Approved Drugs
3401
DrugMAP
DMHKGCM
DM0GZTD
Enamine Bioactive Compounds
EBC-03972
Enamine BioReference Compounds
Guide to Pharmacology
725
MedChem Express Bioactive Compound Library
HY-B1352
HY-131514
HY-W017018
NPC Screening Collection
ReFrame library
Selleckchem Bioactive Compound Library
l-ornithine
l-ornithine-hydrochloride
TargetMol Bioactive Compound Library
T0737
T21024
T2O2701
T19399
External IDs
117
Properties
(calculated by RDKit )
Molecular Weight
132.09
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
3
Rotatable Bonds
4
Ring Count
0
Aromatic Ring Count
0
cLogP
-0.86
TPSA
89.34
Fraction CSP3
0.8
Chiral centers
1.0
Largest ring
0.0
QED
0.46
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Arginase-1
Arginase-2
Endogenous Metabolite
Ornithine aminotransferase
Ornithine carbamoyltransferase
Ornithine decarboxylase antizyme 1
GHR
Insulin Receptor
MOA
Amino Acids and Derivatives
Arginase
Decarboxylase
Pathway
Immunology/Inflammation
Metabolism
Metabolic Enzyme/Protease
Protein Tyrosine Kinase/RTK
Source data