General
Preferred name
ADENOSINE PHOSPHATE
Synonyms
5'-AMP ()
5'-AMP monohydrate ()
5'-Adenylic acid ()
AMP ()
adenosine 5'-monophosphate ()
Adenosine Phosphate Disodium ()
5'-AMP-NA2 ()
Adenosine 5'-monophosphate monohydrate ()
Adenosine monophosphate ()
Polyadenylic polyuridylic acid ()
5'-Adenylic acid, 5'-AMP ()
AMP, Adenosine monophosphate ()
Adenosine 5'-monophosphate disodium salt ()
Adenosine 5'-monophosphate (sodium salt hydrate) ()
A 5MP ()
Adenosine monophosphate (amp) ()
Phosphate d'adenosine ()
Fosfato de adenosina ()
Adenyl ()
Adenosine 5'-monophosphoric acid ()
NSC-20264 ()
Vitamin B8 ()
5'-adenylic acid ()
A-5MP ()
Adenosine 5'-​monophosphate ()
P&D ID
PD010227
CAS
18422-05-4
13270-66-1
55036-25-4
162756-82-3
34051-12-2
24937-83-5
61-19-8
4578-31-8
149022-20-8
Tags
available
drug
Drug indication
Malnutrition
Ischemia
Drug Status
approved
withdrawn
investigational
nutraceutical
Max Phase
4.0
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE 29
PRICE 29
PRICE 29
DESCRIPTION Adenosine 5'-monophosphate monohydrate (5'-AMP) , also known as 5'-adenylic acid, is a nucleotide that is used as a monomer in RNA. It is an ester of phosphoric acid and the nucleoside adenosine. Adenosine 5'-monophosphate monohydrate consists of a phosphate group, the sugar ribose, and the nucleobase adenine. As a substituent it takes the form of the prefix adenylyl-. (TargetMol Bioactive Compound Library)
DESCRIPTION Adenosine monophosphate is a nucleotide that is found in RNA. It is used for nutritional supplementation, also for treating dietary shortage or imbalance. (Enamine Bioactive Compounds)
DESCRIPTION Adenosine monophosphate (AMP) is a purine ribonucleoside 5'-monophosphates and a key cellular metabolite in signal transduction and regulation of energy homeostasis.It has a role as an EC 3.1.3.11 (fructose-bisphosphatase) inhibitor, an EC 3.1.3.1 (alkaline phosphatase) inhibitor and an adenosine A1 receptor agonist. (TargetMol Bioactive Compound Library)
DESCRIPTION Adenosine 5'-monophosphate disodium salt (Adenosine Phosphate Disodium) is a purine nucleotide involved in ATP metabolism and is used to study the effects of ATP on cells and organisms. Adenosine 5'-monophosphate disodium salt has been shown to have a variety of biochemical and physiological effects. It has been shown to increase cell metabolism, gene expression, and protein synthesis. (TargetMol Bioactive Compound Library)
Compound Sets
26
Cayman Chemical Bioactives
21094
ChEMBL Approved Drugs
CHEMBL752
ChEMBL Drugs
CHEMBL752
Concise Guide to Pharmacology 2017/18
2455
Concise Guide to Pharmacology 2019/20
2455
Concise Guide to Pharmacology 2021/22
2455
Concise Guide to Pharmacology 2023/24
2455
CZ-OPENSCREEN Bioactive Library
Drug Repurposing Hub
DrugBank
DB00131
DrugBank Approved Drugs
DB00131
DrugCentral
92
DrugCentral Approved Drugs
92
DrugMAP
DMNIJT0
DrugMAP Approved Drugs
DMNIJT0
Enamine Bioactive Compounds
EBC-26679
EU-OPENSCREEN Bioactive Compound Library
EOS101155
Guide to Pharmacology
2455
LSP-MoA library (Laboratory of Systems Pharmacology)
CHEMBL752
LSP-OptimalKinase library (Laboratory of Systems Pharmacology)
CHEMBL752
Novartis Chemogenetic Library (NIBR MoA Box)
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
adenosine-5-monophosphate-monohydrate
5-adenylic-acid
TargetMol Bioactive Compound Library
T0853L
T2133
T65979
Withdrawn 2.0
w253
External IDs
99
Properties
(calculated by RDKit )
Molecular Weight
347.06
Hydrogen Bond Acceptors
10
Hydrogen Bond Donors
5
Rotatable Bonds
4
Ring Count
3
Aromatic Ring Count
2
cLogP
-1.86
TPSA
186.07
Fraction CSP3
0.5
Chiral centers
4.0
Largest ring
6.0
QED
0.39
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
5'-AMP-activated protein kinase
Endogenous Metabolite
Nucleoside
ACSL1, ACSS1, ACSS2, ADCY1, ADK, CREB1, FBP1, HINT1, PDE4B, PDE4D, PIM1, PRKAA1, PRKAB1, PRKAB2, PYGL, TRPM4
Adenosine Receptor
HSV
Pathway
Chromatin/Epigenetic
GPCR/G protein
Microbiology/virology
Neuroscience
PI3K/Akt/mTOR signaling
Metabolism
Cell Cycle/Checkpoint
DNA Damage/DNA Repair
MOA
AMPK
nucleotide
AMPK activator
"nucleotide
AMPK Activator"
Adenosine Receptor agonist
Member status
member
ATC
V
Toxicity type
cardiovascular
Therapeutic Class
Dietary supplement
Source data